Human Gene FAM156B (uc004drl.3)
  Description: Homo sapiens family with sequence similarity 156, member A (FAM156B), transcript variant 4, mRNA.
Transcript (Including UTRs)
   Position: hg19 chrX:52,928,085-52,937,585 Size: 9,501 Total Exon Count: 3 Strand: +
Coding Region
   Position: hg19 chrX:52,936,253-52,936,894 Size: 642 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsPrimersGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chrX:52,928,085-52,937,585)mRNA (may differ from genome)Protein (213 aa)
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PubMedUniProtKBWikipediaBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: FA156_HUMAN
DESCRIPTION: RecName: Full=Protein FAM156A/FAM156B; AltName: Full=Transmembrane protein 29;
SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein (Potential).
SEQUENCE CAUTION: Sequence=AAF24055.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAH00867.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 1.99 RPKM in Pituitary
Total median expression: 38.88 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -252.50690-0.366 Picture PostScript Text
3' UTR -245.93691-0.356 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF15549 - PGC7/Stella/Dppa3 domain

ModBase Predicted Comparative 3D Structure on Q8NDB6
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding
GO:0035064 methylated histone binding

Cellular Component:
GO:0005635 nuclear envelope
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  AK057692 - Homo sapiens cDNA FLJ33130 fis, clone UMVEN1000122, highly similar to Transmembrane protein 29.
BX649013 - Homo sapiens mRNA; cDNA DKFZp686H1294 (from clone DKFZp686H1294).
AK091598 - Homo sapiens cDNA FLJ34279 fis, clone FEBRA2003833, highly similar to Transmembrane protein 29.
AX747084 - Sequence 609 from Patent EP1308459.
AK092365 - Homo sapiens cDNA FLJ35046 fis, clone OCBBF2017791, highly similar to Transmembrane protein 29.
AX747504 - Sequence 1029 from Patent EP1308459.
AK096162 - Homo sapiens cDNA FLJ38843 fis, clone MESAN2003646, highly similar to Transmembrane protein 29.
AF370413 - Homo sapiens PP12994 mRNA, complete cds.
JD308309 - Sequence 289333 from Patent EP1572962.
AL834135 - Homo sapiens mRNA; cDNA DKFZp667C0711 (from clone DKFZp667C0711); complete cds.
JD347145 - Sequence 328169 from Patent EP1572962.
JD278089 - Sequence 259113 from Patent EP1572962.
JD216735 - Sequence 197759 from Patent EP1572962.
JD210816 - Sequence 191840 from Patent EP1572962.
JD566039 - Sequence 547063 from Patent EP1572962.
JD166007 - Sequence 147031 from Patent EP1572962.
JD498669 - Sequence 479693 from Patent EP1572962.
AK054721 - Homo sapiens cDNA FLJ30159 fis, clone BRACE2000526.
JD223596 - Sequence 204620 from Patent EP1572962.
JD260249 - Sequence 241273 from Patent EP1572962.
JD518261 - Sequence 499285 from Patent EP1572962.
JD117854 - Sequence 98878 from Patent EP1572962.
JD139023 - Sequence 120047 from Patent EP1572962.
AB464316 - Synthetic construct DNA, clone: pF1KB7101, Homo sapiens TMEM29 gene for transmembrane protein 29, without stop codon, in Flexi system.
AM393186 - Synthetic construct Homo sapiens clone IMAGE:100001847 for hypothetical protein (TMEM29 gene).
AF090943 - Homo sapiens clone HQ0659 PRO0659 mRNA, complete cds.
BC000867 - Homo sapiens family with sequence similarity 156, member A, mRNA (cDNA clone MGC:4888 IMAGE:3460178), complete cds.
JD037480 - Sequence 18504 from Patent EP1572962.
JD369860 - Sequence 350884 from Patent EP1572962.
JD252087 - Sequence 233111 from Patent EP1572962.
JD482213 - Sequence 463237 from Patent EP1572962.
JD251532 - Sequence 232556 from Patent EP1572962.
JD282473 - Sequence 263497 from Patent EP1572962.
JD409102 - Sequence 390126 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: B3KQ92, FA156_HUMAN, FAM156A, NM_001099684, NP_054857, PP12994, PRO0659, Q5JPL2, Q5JPL3, Q5JPL4, Q5JPL5, Q5JPL6, Q68D17, Q6NVY3, Q8NDB6, Q9UI49, TMEM29, TMEM29B
UCSC ID: uc004drl.3
RefSeq Accession: NM_001099684
Protein: Q8NDB6 (aka FA156_HUMAN)
CCDS: CCDS43957.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001099684.1
exon count: 3CDS single in 3' UTR: no RNA size: 1701
ORF size: 642CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1142.00frame shift in genome: no % Coverage: 99.88
has start codon: yes stop codon in genome: no # of Alignments: 2
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.