Human Gene ZNF250 (uc003zer.4)
Description: Homo sapiens zinc finger protein 250 (ZNF250), transcript variant 2, mRNA.Transcript (Including UTRs) Position: hg19 chr8:146,102,336-146,126,846 Size: 24,511 Total Exon Count: 6 Strand: -Coding Region Position: hg19 chr8:146,106,900-146,115,734 Size: 8,835 Coding Exon Count: 5
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR001909 - Krueppel-associated_boxIPR007087 - Znf_C2H2IPR015880 - Znf_C2H2-likeIPR013087 - Znf_C2H2/integrase_DNA-bdPfam Domains: PF00096 - Zinc finger, C2H2 typePF01352 - KRAB boxPF12874 - Zinc-finger of C2H2 typePF13912 - C2H2-type zinc fingerSCOP Domains: 48695 - Multiheme cytochromes109640 - KRAB domain (Kruppel-associated box, Pfam 01352)57667 - C2H2 and C2HC zinc fingersModBase Predicted Comparative 3D Structure on D3DWP1 The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog Gene Details Gene Sorter
Descriptions from all associated GenBank mRNAs
KJ903021 - Synthetic construct Homo sapiens clone ccsbBroadEn_12415 ZNF250 gene, encodes complete protein.JD440367 - Sequence 421391 from Patent EP1572962.AK294282 - Homo sapiens cDNA FLJ57354 complete cds, highly similar to Zinc finger protein 250.BC107579 - Homo sapiens zinc finger protein 250, mRNA (cDNA clone IMAGE:4338057), complete cds.JD413788 - Sequence 394812 from Patent EP1572962.JD463216 - Sequence 444240 from Patent EP1572962.JD337675 - Sequence 318699 from Patent EP1572962.JD352538 - Sequence 333562 from Patent EP1572962.JD448607 - Sequence 429631 from Patent EP1572962.AK095705 - Homo sapiens cDNA FLJ38386 fis, clone FEBRA2004053, moderately similar to ZINC FINGER PROTEIN 84.AB208810 - Homo sapiens mRNA for zinc finger protein 250 variant protein.BC017091 - Homo sapiens zinc finger protein 250, mRNA (cDNA clone MGC:9718 IMAGE:3851128), complete cds.AK054888 - Homo sapiens cDNA FLJ30326 fis, clone BRACE2007174, highly similar to Zinc finger protein 250.X16282 - Human mRNA for zinc finger protein (clone 647).JD360192 - Sequence 341216 from Patent EP1572962.JD437247 - Sequence 418271 from Patent EP1572962.JD199059 - Sequence 180083 from Patent EP1572962.AB384739 - Synthetic construct DNA, clone: pF1KB3061, Homo sapiens ZNF250 gene for zinc finger protein 250, complete cds, without stop codon, in Flexi system.JD047389 - Sequence 28413 from Patent EP1572962.BX648173 - Homo sapiens mRNA; cDNA DKFZp313F1134 (from clone DKFZp313F1134).
Other Names for This Gene
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_001109689.3
exon count:
6 CDS single in 3' UTR:
no
RNA size:
6367 ORF size:
1668 CDS single in intron:
no
Alignment % ID:
100.00 txCdsPredict score:
3512.00 frame shift in genome:
no
% Coverage:
99.72 has start codon:
yes
stop codon in genome:
no
# of Alignments:
1 has end codon:
yes
retained intron:
no
# AT/AC introns
0 selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.
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