ID:PLAC1_HUMAN DESCRIPTION: RecName: Full=Placenta-specific protein 1; Flags: Precursor; FUNCTION: May play a role in placental development. SUBCELLULAR LOCATION: Secreted (Probable). TISSUE SPECIFICITY: Expressed in placenta. Localizes primarily to differentiated syncytiotrophoblast throughout gestation as well as to a small population of villous cytotrophoblasts. Also detected in maternal blood and rapidly disappears following delivery, but is not detected in other adult or fetal tissues examined. INDUCTION: Up-regulated during trophoblast differentiation and by FGF7 in trophoblast cells. SIMILARITY: Belongs to the PLAC1 family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
ModBase Predicted Comparative 3D Structure on Q9HBJ0
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
