Human Gene ABHD13 (uc001vqq.3)
Description: Homo sapiens abhydrolase domain containing 13 (ABHD13), mRNA.
Transcript (Including UTRs)
Position: hg19 chr13:108,870,763-108,886,603 Size: 15,841 Total Exon Count: 2 Strand: +
Coding Region
Position: hg19 chr13:108,881,567-108,882,580 Size: 1,014 Coding Exon Count: 1
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: ABHDD_HUMAN
DESCRIPTION: RecName: Full=Alpha/beta hydrolase domain-containing protein 13; Short=Abhydrolase domain-containing protein 13; EC=3.-.-.-;
SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein (Potential).SIMILARITY: Belongs to the serine esterase family.SEQUENCE CAUTION: Sequence=AAH70226.1; Type=Erroneous initiation; Sequence=AK075195; Type=Erroneous termination; Positions=167; Note=Translated as Leu; Sequence=BAB55387.1; Type=Erroneous initiation;
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): ABHD13
CDC HuGE Published Literature: ABHD13
Positive Disease Associations: Attention deficit hyperactivity disorder and conduct disorder
Related Studies: Attention deficit hyperactivity disorder and conduct disorder Anney ,et al. 2008, Conduct disorder and ADHD: Evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study, American journal of medical genetics. Part B, Neuropsychiatric genetics 2008 147B- 8 : 1369-78.
[PubMed 18951430 ]
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF00561 - alpha/beta hydrolase fold
PF05448 - Acetyl xylan esterase (AXE1)
PF12146 - Serine aminopeptidase, S33
SCOP Domains: 53474 - alpha/beta-Hydrolases
ModBase Predicted Comparative 3D Structure on Q7L211
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
LF208024 - JP 2014500723-A/15527: Polycomb-Associated Non-Coding RNAs.AK075195 - Homo sapiens cDNA FLJ90714 fis, clone PLACE1008359.BC022566 - Homo sapiens abhydrolase domain containing 13, mRNA (cDNA clone MGC:27058 IMAGE:4811611), complete cds.LF371066 - JP 2014500723-A/178569: Polycomb-Associated Non-Coding RNAs.AK124864 - Homo sapiens cDNA FLJ42874 fis, clone BRHIP2026288, weakly similar to Protein bem46.BX647428 - Homo sapiens mRNA; cDNA DKFZp686P09144 (from clone DKFZp686P09144).LF371069 - JP 2014500723-A/178572: Polycomb-Associated Non-Coding RNAs.BC070226 - Homo sapiens abhydrolase domain containing 13, mRNA (cDNA clone MGC:88207 IMAGE:6716889), complete cds.AK027812 - Homo sapiens cDNA FLJ14906 fis, clone PLACE1005890, weakly similar to BEM46 PROTEIN.KJ903495 - Synthetic construct Homo sapiens clone ccsbBroadEn_12889 ABHD13 gene, encodes complete protein.LF371070 - JP 2014500723-A/178573: Polycomb-Associated Non-Coding RNAs.LF371071 - JP 2014500723-A/178574: Polycomb-Associated Non-Coding RNAs.LF371072 - JP 2014500723-A/178575: Polycomb-Associated Non-Coding RNAs.LF371073 - JP 2014500723-A/178576: Polycomb-Associated Non-Coding RNAs.JD087694 - Sequence 68718 from Patent EP1572962.JD486838 - Sequence 467862 from Patent EP1572962.JD291111 - Sequence 272135 from Patent EP1572962.JD490922 - Sequence 471946 from Patent EP1572962.LF371074 - JP 2014500723-A/178577: Polycomb-Associated Non-Coding RNAs.JD094563 - Sequence 75587 from Patent EP1572962.JD206382 - Sequence 187406 from Patent EP1572962.JD239443 - Sequence 220467 from Patent EP1572962.JD103612 - Sequence 84636 from Patent EP1572962.BC018608 - Homo sapiens abhydrolase domain containing 13, mRNA (cDNA clone IMAGE:3918528).JD114682 - Sequence 95706 from Patent EP1572962.MA606643 - JP 2018138019-A/178569: Polycomb-Associated Non-Coding RNAs.MA606646 - JP 2018138019-A/178572: Polycomb-Associated Non-Coding RNAs.MA606647 - JP 2018138019-A/178573: Polycomb-Associated Non-Coding RNAs.MA606648 - JP 2018138019-A/178574: Polycomb-Associated Non-Coding RNAs.MA606649 - JP 2018138019-A/178575: Polycomb-Associated Non-Coding RNAs.MA606650 - JP 2018138019-A/178576: Polycomb-Associated Non-Coding RNAs.MA606651 - JP 2018138019-A/178577: Polycomb-Associated Non-Coding RNAs.MA443601 - JP 2018138019-A/15527: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Alternate Gene Symbols: ABHDD_HUMAN, B3KWE7, C13orf6, NM_032859, NP_116248, Q7L211, Q8NBW1, Q96JX9UCSC ID: uc001vqq.3RefSeq Accession: NM_032859
Protein: Q7L211
(aka ABHDD_HUMAN)
CCDS: CCDS32007.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_032859.2
exon count:
2 CDS single in 3' UTR:
no
RNA size:
5316
ORF size:
1014 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
2007.00 frame shift in genome:
no
% Coverage:
99.74
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.