Description: Homo sapiens cyclin-dependent kinase 16 (CDK16), transcript variant 3, mRNA. RefSeq Summary (NM_001170460): The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2009]. Transcript (Including UTRs) Position: hg19 chrX:47,082,417-47,089,394 Size: 6,978 Total Exon Count: 16 Strand: + Coding Region Position: hg19 chrX:47,082,495-47,088,167 Size: 5,673 Coding Exon Count: 16
ID:J3KN74_HUMAN DESCRIPTION: SubName: Full=Cyclin-dependent kinase 16; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF00069 - Protein kinase domain PF07714 - Protein tyrosine kinase PF14531 - Kinase-like
SCOP Domains: 56112 - Protein kinase-like (PK-like)
ModBase Predicted Comparative 3D Structure on J3KN74
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
