Human Gene RPL7L1 (uc003osq.1)
  Description: Homo sapiens ribosomal protein L7-like 1 (RPL7L1), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr6:42,847,671-42,854,731 Size: 7,061 Total Exon Count: 6 Strand: +
Coding Region
   Position: hg19 chr6:42,847,676-42,854,202 Size: 6,527 Coding Exon Count: 6 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr6:42,847,671-42,854,731)mRNA (may differ from genome)Protein (246 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
H-INVHGNCHPRDLynxMGIneXtProt
OMIMPubMedUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: RL7L_HUMAN
DESCRIPTION: RecName: Full=60S ribosomal protein L7-like 1;
INTERACTION: P49407:ARRB1; NbExp=1; IntAct=EBI-1052408, EBI-743313; P32121:ARRB2; NbExp=1; IntAct=EBI-1052408, EBI-714559;
SIMILARITY: Belongs to the ribosomal protein L30P family.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 28.26 RPKM in Cells - Cultured fibroblasts
Total median expression: 750.23 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
3' UTR -191.60529-0.362 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR018038 - Ribosomal_L30_CS
IPR016082 - Ribosomal_L30_ferredoxin-like
IPR012988 - Ribosomal_L30_N
IPR005998 - Ribosomal_L7_euk

Pfam Domains:
PF00327 - Ribosomal protein L30p/L7e
PF08079 - Ribosomal L30 N-terminal domain

SCOP Domains:
55129 - Ribosomal protein L30p/L7e

ModBase Predicted Comparative 3D Structure on Q6DKI1
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome

Biological Process:
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0001825 blastocyst formation
GO:0002181 cytoplasmic translation

Cellular Component:
GO:0005730 nucleolus
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit


-  Descriptions from all associated GenBank mRNAs
  BC064519 - Homo sapiens ribosomal protein L7-like 1, mRNA (cDNA clone IMAGE:5574226), partial cds.
BC036861 - Homo sapiens ribosomal protein L7-like 1, mRNA (cDNA clone IMAGE:5115021), containing frame-shift errors.
AK291310 - Homo sapiens cDNA FLJ77818 complete cds.
AK299816 - Homo sapiens cDNA FLJ50850 complete cds, highly similar to Ribosomal protein L7-like 1.
AK091341 - Homo sapiens cDNA FLJ34022 fis, clone FCBBF2002953.
AK297324 - Homo sapiens cDNA FLJ51993 complete cds, highly similar to Ribosomal protein L7-like 1.
AK291949 - Homo sapiens cDNA FLJ76625 complete cds, highly similar to Homo sapiens ribosomal protein L7-like 1 (RPL7L1), mRNA.
BC058020 - Homo sapiens ribosomal protein L7-like 1, mRNA (cDNA clone MGC:62004 IMAGE:6736635), complete cds.
AK021904 - Homo sapiens cDNA FLJ11842 fis, clone HEMBA1006652, highly similar to Ribosomal protein L7-like 1.
BC073890 - Homo sapiens ribosomal protein L7-like 1, mRNA (cDNA clone MGC:90362 IMAGE:5491531), complete cds.
LF385200 - JP 2014500723-A/192703: Polycomb-Associated Non-Coding RNAs.
EU832458 - Synthetic construct Homo sapiens clone HAIB:100067487; DKFZo008B0629 ribosomal protein L7-like 1 protein (RPL7L1) gene, encodes complete protein.
CU687268 - Synthetic construct Homo sapiens gateway clone IMAGE:100022755 5' read RPL7L1 mRNA.
HQ447443 - Synthetic construct Homo sapiens clone IMAGE:100070771; CCSB014347_01 ribosomal protein L7-like 1 (RPL7L1) gene, encodes complete protein.
KJ896015 - Synthetic construct Homo sapiens clone ccsbBroadEn_05409 RPL7L1 gene, encodes complete protein.
EU832540 - Synthetic construct Homo sapiens clone HAIB:100067569; DKFZo004B0630 ribosomal protein L7-like 1 protein (RPL7L1) gene, encodes complete protein.
JD085293 - Sequence 66317 from Patent EP1572962.
JD019359 - Sequence 383 from Patent EP1572962.
JD032590 - Sequence 13614 from Patent EP1572962.
DQ583593 - Homo sapiens piRNA piR-50705, complete sequence.
DQ573947 - Homo sapiens piRNA piR-42059, complete sequence.
JD221598 - Sequence 202622 from Patent EP1572962.
JD278474 - Sequence 259498 from Patent EP1572962.
JD265637 - Sequence 246661 from Patent EP1572962.
JD291948 - Sequence 272972 from Patent EP1572962.
JD447439 - Sequence 428463 from Patent EP1572962.
JD092736 - Sequence 73760 from Patent EP1572962.
JD545412 - Sequence 526436 from Patent EP1572962.
JD504289 - Sequence 485313 from Patent EP1572962.
JD208953 - Sequence 189977 from Patent EP1572962.
JD076468 - Sequence 57492 from Patent EP1572962.
JD548096 - Sequence 529120 from Patent EP1572962.
JD376725 - Sequence 357749 from Patent EP1572962.
JD417586 - Sequence 398610 from Patent EP1572962.
JD417587 - Sequence 398611 from Patent EP1572962.
JD417588 - Sequence 398612 from Patent EP1572962.
JD289575 - Sequence 270599 from Patent EP1572962.
JD411821 - Sequence 392845 from Patent EP1572962.
JD411822 - Sequence 392846 from Patent EP1572962.
JD196471 - Sequence 177495 from Patent EP1572962.
JD144138 - Sequence 125162 from Patent EP1572962.
JD495947 - Sequence 476971 from Patent EP1572962.
JD532504 - Sequence 513528 from Patent EP1572962.
JD136159 - Sequence 117183 from Patent EP1572962.
JD079525 - Sequence 60549 from Patent EP1572962.
JD487482 - Sequence 468506 from Patent EP1572962.
JD065891 - Sequence 46915 from Patent EP1572962.
JD180068 - Sequence 161092 from Patent EP1572962.
JD196829 - Sequence 177853 from Patent EP1572962.
JD179044 - Sequence 160068 from Patent EP1572962.
JD074823 - Sequence 55847 from Patent EP1572962.
JD179045 - Sequence 160069 from Patent EP1572962.
JD361165 - Sequence 342189 from Patent EP1572962.
JD333770 - Sequence 314794 from Patent EP1572962.
JD183875 - Sequence 164899 from Patent EP1572962.
JD092046 - Sequence 73070 from Patent EP1572962.
JD292439 - Sequence 273463 from Patent EP1572962.
JD534478 - Sequence 515502 from Patent EP1572962.
JD451670 - Sequence 432694 from Patent EP1572962.
JD364935 - Sequence 345959 from Patent EP1572962.
JD461402 - Sequence 442426 from Patent EP1572962.
JD405409 - Sequence 386433 from Patent EP1572962.
JD185466 - Sequence 166490 from Patent EP1572962.
MA620777 - JP 2018138019-A/192703: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: A8K7D4, NM_198486, NP_940888, Q5TFZ5, Q6DKI1, Q6PEK3, RL7L_HUMAN
UCSC ID: uc003osq.1
RefSeq Accession: NM_198486
Protein: Q6DKI1 (aka RL7L_HUMAN)
CCDS: CCDS4873.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_198486.2
exon count: 6CDS single in 3' UTR: no RNA size: 1293
ORF size: 741CDS single in intron: no Alignment % ID: 99.92
txCdsPredict score: 1676.00frame shift in genome: no % Coverage: 98.61
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 523# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.