Human Gene UBE2W (uc031tbk.1) Description and Page Index
  Description: Homo sapiens ubiquitin-conjugating enzyme E2W (putative) (UBE2W), transcript variant 5, non-coding RNA.
RefSeq Summary (NR_073120): This gene encodes a nuclear-localized ubiquitin-conjugating enzyme (E2) that, along with ubiquitin-activating (E1) and ligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. The encoded protein promotes the ubiquitination of Fanconi anemia complementation group proteins and may be important in the repair of DNA damage. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
Transcript (Including UTRs)
   Position: hg19 chr8:74,698,455-74,791,145 Size: 92,691 Total Exon Count: 6 Strand: -


Page IndexSequence and LinksCTDRNA-Seq ExpressionMicroarray ExpressionOther Species
mRNA DescriptionsPathwaysOther NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr8:74,698,455-74,791,145)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerH-INVHGNC
LynxOMIMPubMedStanford SOURCE

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 5.43 RPKM in Brain - Cerebellar Hemisphere
Total median expression: 175.39 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  BC010900 - Homo sapiens ubiquitin-conjugating enzyme E2W (putative), mRNA (cDNA clone MGC:13396 IMAGE:4081461), complete cds.
LP895601 - Sequence 465 from Patent EP3253886.
KJ902804 - Synthetic construct Homo sapiens clone ccsbBroadEn_12198 UBE2W gene, encodes complete protein.
EU446497 - Synthetic construct Homo sapiens clone IMAGE:100070043; IMAGE:100011706; FLH257402.01L ubiquitin-conjugating enzyme E2W (putative) (UBE2W) gene, encodes complete protein.
BX648427 - Homo sapiens mRNA; cDNA DKFZp686A06253 (from clone DKFZp686A06253).
BX538145 - Homo sapiens mRNA; cDNA DKFZp686B0374 (from clone DKFZp686B0374).
AK001873 - Homo sapiens cDNA FLJ11011 fis, clone PLACE1003174, moderately similar to UBIQUITIN-CONJUGATING ENZYME E2-18 KD (EC 6.3.2.19).
AY948289 - Homo sapiens ubiquitin-conjugating enzyme 16 mRNA, complete cds.
AK021735 - Homo sapiens cDNA FLJ11673 fis, clone HEMBA1004734, moderately similar to UBIQUITIN-CONJUGATING ENZYME E2-18 KD (EC 6.3.2.19).
BC016326 - Homo sapiens ubiquitin-conjugating enzyme E2W (putative), mRNA (cDNA clone MGC:23711 IMAGE:4093131), complete cds.
AK024050 - Homo sapiens cDNA FLJ13988 fis, clone Y79AA1002027, moderately similar to UBIQUITIN-CONJUGATING ENZYME E2-18 KD (EC 6.3.2.19).
AK225554 - Homo sapiens mRNA for hypothetical protein LOC55284 isoform 2 variant, clone: KDN04471.
AK295792 - Homo sapiens cDNA FLJ56326 complete cds, highly similar to Probable ubiquitin-conjugating enzyme E2 W(EC 6.3.2.19).
AK123531 - Homo sapiens cDNA FLJ41537 fis, clone BRTHA2017985.
JD218794 - Sequence 199818 from Patent EP1572962.
JD089090 - Sequence 70114 from Patent EP1572962.
JD414792 - Sequence 395816 from Patent EP1572962.
JD397043 - Sequence 378067 from Patent EP1572962.
JD476721 - Sequence 457745 from Patent EP1572962.
JD094107 - Sequence 75131 from Patent EP1572962.
JD256537 - Sequence 237561 from Patent EP1572962.
JD120550 - Sequence 101574 from Patent EP1572962.
JD379645 - Sequence 360669 from Patent EP1572962.
JD379646 - Sequence 360670 from Patent EP1572962.
JD120549 - Sequence 101573 from Patent EP1572962.
JD414791 - Sequence 395815 from Patent EP1572962.
JD379644 - Sequence 360668 from Patent EP1572962.
JD414790 - Sequence 395814 from Patent EP1572962.
JD090948 - Sequence 71972 from Patent EP1572962.
JD303842 - Sequence 284866 from Patent EP1572962.
JD553764 - Sequence 534788 from Patent EP1572962.
JD046775 - Sequence 27799 from Patent EP1572962.
JD226252 - Sequence 207276 from Patent EP1572962.
JD168272 - Sequence 149296 from Patent EP1572962.
JD270155 - Sequence 251179 from Patent EP1572962.
JD217404 - Sequence 198428 from Patent EP1572962.
JD243340 - Sequence 224364 from Patent EP1572962.
JD235025 - Sequence 216049 from Patent EP1572962.
JD166205 - Sequence 147229 from Patent EP1572962.
CR457275 - Homo sapiens full open reading frame cDNA clone RZPDo834E029D for gene FLJ11011, hypothetical protein FLJ11011; complete cds, incl. stopcodon.
KJ894177 - Synthetic construct Homo sapiens clone ccsbBroadEn_03571 UBE2W gene, encodes complete protein.

-  Biochemical and Signaling Pathways
  KEGG - Kyoto Encyclopedia of Genes and Genomes
hsa04120 - Ubiquitin mediated proteolysis

-  Other Names for This Gene
  Alternate Gene Symbols: NR_073120, uc003xzu.3
UCSC ID: uc031tbk.1
RefSeq Accession: NR_073120

-  Gene Model Information
 
category: nearCoding nonsense-mediated-decay: no RNA accession: NR_073120.1
exon count: 6CDS single in 3' UTR: no RNA size: 8407
ORF size: 0CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 240.00frame shift in genome: no % Coverage: 100.00
has start codon: no stop codon in genome: no # of Alignments: 1
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.