Human Gene SAMD11 (uc031pjr.1) Description and Page Index
  Description: Homo sapiens sterile alpha motif domain containing 11 (SAMD11), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr1:861,302-879,961 Size: 18,660 Total Exon Count: 11 Strand: +
Coding Region
   Position: hg19 chr1:877,822-879,533 Size: 1,712 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:861,302-879,961)mRNA (may differ from genome)Protein (342 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
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Stanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: SAM11_HUMAN
DESCRIPTION: RecName: Full=Sterile alpha motif domain-containing protein 11; Short=SAM domain-containing protein 11;
FUNCTION: May play a role in photoreceptor development (By similarity).
SUBUNIT: Homodimer (By similarity).
SUBCELLULAR LOCATION: Nucleus (By similarity).
SIMILARITY: Contains 1 SAM (sterile alpha motif) domain.
SEQUENCE CAUTION: Sequence=AAH24295.1; Type=Frameshift; Positions=129; Sequence=BAB70781.1; Type=Erroneous initiation; Sequence=CAI15563.3; Type=Erroneous gene model prediction; Sequence=CAI15564.3; Type=Erroneous gene model prediction;

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 15.02 RPKM in Pituitary
Total median expression: 104.00 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -326.82701-0.466 Picture PostScript Text
3' UTR -172.00428-0.402 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001660 - SAM
IPR013761 - SAM/pointed
IPR011510 - SAM_2

Pfam Domains:
PF00536 - SAM domain (Sterile alpha motif)
PF07647 - SAM domain (Sterile alpha motif)

SCOP Domains:
47769 - SAM/Pointed domain

ModBase Predicted Comparative 3D Structure on Q96NU1
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0005634 nucleus


-  Descriptions from all associated GenBank mRNAs
  JX093086 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV21 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093066 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV1 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093067 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV2 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093068 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV3 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093069 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV4 (SAMD11) mRNA, partial cds, alternatively spliced.
JX093070 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV5 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093071 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV6 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093072 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV7 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093073 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV8 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093074 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV9 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093075 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV10 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093076 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV11 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093077 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV12 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093078 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV13 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093079 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV14 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093080 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV15 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093081 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV16 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093082 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV17 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093083 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV18 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093084 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV19 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093085 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV20 (SAMD11) mRNA, partial cds, alternatively spliced.
JX093087 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV22 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093088 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV23 (SAMD11) mRNA, partial cds, alternatively spliced.
JX093089 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV24 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093090 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV25 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093091 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV26 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093092 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV27 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093093 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV28 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093094 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV29 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093095 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV30 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093096 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV31 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093097 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV32 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093098 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV33 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093099 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV34 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093100 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV35 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093101 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV36 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093102 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV37 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093103 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV38 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093104 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV39 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093105 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV40 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093106 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV41 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093107 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV42 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093108 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV43 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093109 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV44 (SAMD11) mRNA, complete cds, alternatively spliced.
JX093110 - Homo sapiens sterile alpha motif domain containing 11 splice variant ASV45 (SAMD11) mRNA, complete cds, alternatively spliced.
BC024295 - Homo sapiens sterile alpha motif domain containing 11, mRNA (cDNA clone MGC:39333 IMAGE:3354502), complete cds.
AK054643 - Homo sapiens cDNA FLJ30081 fis, clone BGGI12000693, weakly similar to POLYHOMEOTIC-PROXIMAL CHROMATIN PROTEIN.
KJ905008 - Synthetic construct Homo sapiens clone ccsbBroadEn_14402 SAMD11-like gene, encodes complete protein.
BC033213 - Homo sapiens sterile alpha motif domain containing 11, mRNA (cDNA clone MGC:45873 IMAGE:5014368), complete cds.
BX648399 - Homo sapiens mRNA; cDNA DKFZp686M11224 (from clone DKFZp686M11224).
JD093801 - Sequence 74825 from Patent EP1572962.
JD165567 - Sequence 146591 from Patent EP1572962.
JD294631 - Sequence 275655 from Patent EP1572962.
JD484184 - Sequence 465208 from Patent EP1572962.
JD206232 - Sequence 187256 from Patent EP1572962.
JD332976 - Sequence 314000 from Patent EP1572962.
JD329721 - Sequence 310745 from Patent EP1572962.
JD141740 - Sequence 122764 from Patent EP1572962.
JD134773 - Sequence 115797 from Patent EP1572962.
JD460195 - Sequence 441219 from Patent EP1572962.
JD427098 - Sequence 408122 from Patent EP1572962.
JD115071 - Sequence 96095 from Patent EP1572962.
JD218626 - Sequence 199650 from Patent EP1572962.
JD097481 - Sequence 78505 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A2AA76, JX093106, Q5SV96, Q5SV99, Q5SVA0, Q8N195, Q8TB59, Q96NU1, SAM11_HUMAN, uc001abw.1
UCSC ID: uc031pjr.1
RefSeq Accession: NM_152486
Protein: Q96NU1 (aka SAM11_HUMAN)

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: JX093106.1
exon count: 11CDS single in 3' UTR: no RNA size: 1710
ORF size: 1029CDS single in intron: no Alignment % ID: 99.94
txCdsPredict score: 755.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
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-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.