Human Gene PRDM7 (uc010cjh.1) Description and Page Index
  Description: Homo sapiens PR domain containing 7 (PRDM7), transcript variant 1, mRNA.
RefSeq Summary (NM_001098173): This gene encodes a member of a family of proteins that may have roles in transcription and other nuclear processes. The encoded protein contains a KRAB (Kruppel-associated box) domain -A box and a SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain and may function as a histone methyltransferase. [provided by RefSeq, Aug 2013]. ##Evidence-Data-START## Transcript exon combination :: AM690991.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2161674 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##
Transcript (Including UTRs)
   Position: hg19 chr16:90,127,860-90,142,338 Size: 14,479 Total Exon Count: 6 Strand: -

Page IndexSequence and LinksGenetic AssociationsCTDRNA-Seq ExpressionMicroarray Expression
Other SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr16:90,127,860-90,142,338)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
LynxPubMedStanford SOURCE

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): PRDM7
CDC HuGE Published Literature: PRDM7
Positive Disease Associations: Heart Failure
Related Studies:
  1. Heart Failure
    , , . [PubMed 0]

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 2.14 RPKM in Testis
Total median expression: 2.33 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog

-  Descriptions from all associated GenBank mRNAs
  AL137711 - Homo sapiens mRNA; cDNA DKFZp434H1323 (from clone DKFZp434H1323).
AF274347 - Homo sapiens PR-domain zinc finger protein 7 isoform A (PRDM7) mRNA, complete cds; alternatively spliced.
AF274348 - Homo sapiens PR-domain zinc finger protein 7 isoform B (PRDM7) mRNA, complete cds; alternatively spliced.
AM690993 - Homo sapiens partial mRNA for PRDM7 long isoform, variant 2 (PRDM7_V3 gene).
AM690992 - Homo sapiens partial mRNA for PRDM7 long isoform, variant 2 (PRDM7_V2 gene).
AM690991 - Homo sapiens partial mRNA for PRDM7 long isoform, variant 1 (PRDM7_V1 gene).
BC107033 - Homo sapiens PR domain containing 7, mRNA (cDNA clone IMAGE:40000087), complete cds.
KJ893227 - Synthetic construct Homo sapiens clone ccsbBroadEn_02621 PRDM7 gene, encodes complete protein.
AB527979 - Synthetic construct DNA, clone: pF1KB7533, Homo sapiens PRDM7 gene for PR domain containing protein 7, without stop codon, in Flexi system.

-  Other Names for This Gene
  Alternate Gene Symbols: AM690992
UCSC ID: uc010cjh.1
RefSeq Accession: NM_001098173

-  Gene Model Information
category: nearCoding nonsense-mediated-decay: yes RNA accession: AM690992.1
exon count: 6CDS single in 3' UTR: no RNA size: 1464
ORF size: 0CDS single in intron: no Alignment % ID: 99.79
txCdsPredict score: 634.00frame shift in genome: no % Coverage: 48.22
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.