Human Gene RPS6KC1 (uc009xdi.1) Description and Page Index
Description: Homo sapiens ribosomal protein S6 kinase, 52kDa, polypeptide 1 (RPS6KC1), transcript variant 1, mRNA. RefSeq Summary (NM_012424): Sphingosine kinase catalyzes the formation of sphingosine 1 phosphate, a lipid cellular messenger. The protein encoded by this gene can bind to sphingosine kinase and to phosphatidylinositol 3-phosphate, suggesting a role in sphingosine 1 phophate signaling. The encoded protein can also bind to peroxiredoxin-3 and may help transport it to mitochondria. [provided by RefSeq, Mar 2017]. Transcript (Including UTRs) Position: hg19 chr1:213,234,724-213,244,383 Size: 9,660 Total Exon Count: 2 Strand: +
Press "+" in the title bar above to open this section.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Descriptions from all associated GenBank mRNAs
AK122989 - Homo sapiens cDNA FLJ16747 fis, clone FCBBF3008159, highly similar to Ribosomal protein S6 kinase delta-1 (EC 22.214.171.124). AK299298 - Homo sapiens cDNA FLJ50840 complete cds, highly similar to Ribosomal protein S6 kinase delta-1 (EC 126.96.36.199). AF477978 - Homo sapiens RSK-like protein (RPK118) mRNA, complete cds. BC104769 - Homo sapiens ribosomal protein S6 kinase, 52kDa, polypeptide 1, mRNA (cDNA clone MGC:132429 IMAGE:8143772), complete cds. BC143449 - Homo sapiens cDNA clone IMAGE:9051957, with apparent retained intron. BC143473 - Homo sapiens cDNA clone IMAGE:9051981. BC143474 - Homo sapiens cDNA clone IMAGE:9051982, containing frame-shift errors. AB070706 - Homo sapiens RPK118 mRNA for RSK-like protein, complete cds. EF491805 - Homo sapiens clone RPS6KC1 mRNA, partial sequence; alternatively spliced.