Human Gene DBNDD1 (uc002fqf.1) Description and Page Index
  Description: Homo sapiens dysbindin (dystrobrevin binding protein 1) domain containing 1 (DBNDD1), transcript variant 1, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr16:90,071,279-90,085,937 Size: 14,659 Total Exon Count: 4 Strand: -
Coding Region
   Position: hg19 chr16:90,072,743-90,085,749 Size: 13,007 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr16:90,071,279-90,085,937)mRNA (may differ from genome)Protein (158 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
PubMedStanford SOURCETreefamUniProtKB

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Dysbindin domain-containing protein 1;
SIMILARITY: Belongs to the dysbindin family.

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): DBNDD1
CDC HuGE Published Literature: DBNDD1
Positive Disease Associations: Suntan
Related Studies:
  1. Suntan
    Hongmei Nan et al. The Journal of investigative dermatology 2009, Genome-wide association study of tanning phenotype in a population of European ancestry., The Journal of investigative dermatology. [PubMed 19340012]

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 42.76 RPKM in Brain - Cortex
Total median expression: 367.72 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -102.50188-0.545 Picture PostScript Text
3' UTR -585.251464-0.400 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007531 - Dysbindin

Pfam Domains:
PF04440 - Dysbindin (Dystrobrevin binding protein 1)

ModBase Predicted Comparative 3D Structure on Q9H9R9
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserGenome BrowserNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 Protein SequenceProtein Sequence   

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Biological Process:
GO:0031175 neuron projection development

Cellular Component:
GO:0005737 cytoplasm
GO:0030672 synaptic vesicle membrane

-  Descriptions from all associated GenBank mRNAs
  AL713678 - Homo sapiens mRNA; cDNA DKFZp761L2416 (from clone DKFZp761L2416).
BC000700 - Homo sapiens dysbindin (dystrobrevin binding protein 1) domain containing 1, mRNA (cDNA clone MGC:3101 IMAGE:3350198), complete cds.
AK096507 - Homo sapiens cDNA FLJ39188 fis, clone OCBBF2004567.
AK090965 - Homo sapiens cDNA FLJ33646 fis, clone BRAMY2024312.
AX746707 - Sequence 232 from Patent EP1308459.
AK022644 - Homo sapiens cDNA FLJ12582 fis, clone NT2RM4001151.
AK090696 - Homo sapiens cDNA FLJ33377 fis, clone BRACE2006258.
AX746579 - Sequence 104 from Patent EP1308459.
JD402511 - Sequence 383535 from Patent EP1572962.
JD253948 - Sequence 234972 from Patent EP1572962.
JD163968 - Sequence 144992 from Patent EP1572962.
JD455598 - Sequence 436622 from Patent EP1572962.
JD209061 - Sequence 190085 from Patent EP1572962.
JD343608 - Sequence 324632 from Patent EP1572962.
JD456909 - Sequence 437933 from Patent EP1572962.
JD424160 - Sequence 405184 from Patent EP1572962.
JD151459 - Sequence 132483 from Patent EP1572962.
JD151155 - Sequence 132179 from Patent EP1572962.
JD326755 - Sequence 307779 from Patent EP1572962.
JD368590 - Sequence 349614 from Patent EP1572962.
JD426061 - Sequence 407085 from Patent EP1572962.
JD399544 - Sequence 380568 from Patent EP1572962.
JD123063 - Sequence 104087 from Patent EP1572962.
JD286347 - Sequence 267371 from Patent EP1572962.
JD437060 - Sequence 418084 from Patent EP1572962.
JD190739 - Sequence 171763 from Patent EP1572962.
JD423805 - Sequence 404829 from Patent EP1572962.
JD340265 - Sequence 321289 from Patent EP1572962.
JD118234 - Sequence 99258 from Patent EP1572962.
JD386507 - Sequence 367531 from Patent EP1572962.
JD211960 - Sequence 192984 from Patent EP1572962.
JD290824 - Sequence 271848 from Patent EP1572962.
JD326992 - Sequence 308016 from Patent EP1572962.
JD061652 - Sequence 42676 from Patent EP1572962.
JD045092 - Sequence 26116 from Patent EP1572962.
JD397496 - Sequence 378520 from Patent EP1572962.
JD336740 - Sequence 317764 from Patent EP1572962.
JD090482 - Sequence 71506 from Patent EP1572962.
JD102654 - Sequence 83678 from Patent EP1572962.
JD371101 - Sequence 352125 from Patent EP1572962.
AK308737 - Homo sapiens cDNA, FLJ98778.
JD218802 - Sequence 199826 from Patent EP1572962.
JD165581 - Sequence 146605 from Patent EP1572962.
JD355285 - Sequence 336309 from Patent EP1572962.
JD492318 - Sequence 473342 from Patent EP1572962.
JD195236 - Sequence 176260 from Patent EP1572962.
JD394767 - Sequence 375791 from Patent EP1572962.
JD441576 - Sequence 422600 from Patent EP1572962.
JD050313 - Sequence 31337 from Patent EP1572962.
AK298932 - Homo sapiens cDNA FLJ59960 complete cds.
JD520179 - Sequence 501203 from Patent EP1572962.
JD123746 - Sequence 104770 from Patent EP1572962.
JD041041 - Sequence 22065 from Patent EP1572962.
JD162588 - Sequence 143612 from Patent EP1572962.
KJ894627 - Synthetic construct Homo sapiens clone ccsbBroadEn_04021 DBNDD1 gene, encodes complete protein.
LF208353 - JP 2014500723-A/15856: Polycomb-Associated Non-Coding RNAs.
LF375202 - JP 2014500723-A/182705: Polycomb-Associated Non-Coding RNAs.
LF212255 - JP 2014500723-A/19758: Polycomb-Associated Non-Coding RNAs.
MA443930 - JP 2018138019-A/15856: Polycomb-Associated Non-Coding RNAs.
MA610779 - JP 2018138019-A/182705: Polycomb-Associated Non-Coding RNAs.
MA447832 - JP 2018138019-A/19758: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: B4DQS3, DBND1_HUMAN, NM_001042610, NP_001036075, Q69YT2, Q9BW25, Q9H9R9
UCSC ID: uc002fqf.1
RefSeq Accession: NM_001042610
Protein: Q9H9R9 (aka DBND1_HUMAN)
CCDS: CCDS42223.1

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NM_001042610.1
exon count: 4CDS single in 3' UTR: no RNA size: 2150
ORF size: 477CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1101.00frame shift in genome: no % Coverage: 99.02
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.