Human Gene MARVELD3 (uc002fau.4) Description and Page Index
  Description: Homo sapiens MARVEL domain containing 3 (MARVELD3), transcript variant 1, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr16:71,660,056-71,675,868 Size: 15,813 Total Exon Count: 3 Strand: +
Coding Region
   Position: hg19 chr16:71,660,133-71,674,930 Size: 14,798 Coding Exon Count: 3 

Page IndexSequence and LinksCTDGene AllelesRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr16:71,660,056-71,675,868)mRNA (may differ from genome)Protein (410 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
H-INVHGNCHPRDLynxMGIOMIM
PubMedStanford SOURCEUniProtKB

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 8.80 RPKM in Small Intestine - Terminal Ileum
Total median expression: 39.91 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -31.6077-0.410 Picture PostScript Text
3' UTR -282.10938-0.301 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q96A59-2
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologGenome BrowserNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
  Ensembl   
  Protein Sequence   
  Alignment   

-  Descriptions from all associated GenBank mRNAs
  LF212239 - JP 2014500723-A/19742: Polycomb-Associated Non-Coding RNAs.
BC005052 - Homo sapiens MARVEL domain containing 3, mRNA (cDNA clone IMAGE:2820819), partial cds.
AK307585 - Homo sapiens cDNA, FLJ97533.
BC011893 - Homo sapiens MARVEL domain containing 3, mRNA (cDNA clone MGC:20498 IMAGE:3942185), complete cds.
BC013376 - Homo sapiens MARVEL domain containing 3, mRNA (cDNA clone MGC:16443 IMAGE:3946889), complete cds.
AK292185 - Homo sapiens cDNA FLJ77508 complete cds, highly similar to Homo sapiens MARVEL domain containing 3 (MARVELD3), transcript variant 1, mRNA.
AK056842 - Homo sapiens cDNA FLJ32280 fis, clone PROST2000176, weakly similar to RD PROTEIN.
CU680584 - Synthetic construct Homo sapiens gateway clone IMAGE:100019242 5' read MARVELD3 mRNA.
HQ447264 - Synthetic construct Homo sapiens clone IMAGE:100070574; CCSB006652_01 MARVEL domain containing 3 (MARVELD3) gene, encodes complete protein.
KJ899929 - Synthetic construct Homo sapiens clone ccsbBroadEn_09323 MARVELD3 gene, encodes complete protein.
LF213141 - JP 2014500723-A/20644: Polycomb-Associated Non-Coding RNAs.
JD537342 - Sequence 518366 from Patent EP1572962.
JD194739 - Sequence 175763 from Patent EP1572962.
JD058298 - Sequence 39322 from Patent EP1572962.
JD220280 - Sequence 201304 from Patent EP1572962.
JD455087 - Sequence 436111 from Patent EP1572962.
JD135932 - Sequence 116956 from Patent EP1572962.
MA447816 - JP 2018138019-A/19742: Polycomb-Associated Non-Coding RNAs.
MA448718 - JP 2018138019-A/20644: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: MRVLDC3, NM_001017967, NP_001017967, Q96A59-2, uc002fau.3
UCSC ID: uc002fau.4
RefSeq Accession: NM_001017967
Protein: Q96A59-2, splice isoform of Q96A59 CCDS: CCDS32478.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001017967.3
exon count: 3CDS single in 3' UTR: no RNA size: 2273
ORF size: 1233CDS single in intron: no Alignment % ID: 99.96
txCdsPredict score: 1845.00frame shift in genome: no % Coverage: 98.90
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.