Human Gene RBM12B (ENST00000627241.1) Description and Page Index
  Description: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. (from UniProt B9ZVT1)
Gencode Transcript: ENST00000627241.1
Gencode Gene: ENSG00000183808.11
Transcript (Including UTRs)
   Position: hg38 chr8:93,733,405-93,736,410 Size: 3,006 Total Exon Count: 2 Strand: -
Coding Region
   Position: hg38 chr8:93,733,405-93,736,410 Size: 3,006 Coding Exon Count: 2 

Page IndexSequence and LinksUniProtKB CommentsMalaCardsCTDRNA-Seq Expression
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr8:93,733,405-93,736,410)mRNA (may differ from genome)Protein (881 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaCGAP
EnsemblExonPrimerGeneCardsHGNCLynxMGI
PubMedStanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: B9ZVT1_HUMAN
DESCRIPTION: SubName: Full=RNA-binding protein 12B;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  MalaCards Disease Associations
  MalaCards Gene Search: RBM12B
Diseases sorted by gene-association score: interleukin-7 receptor alpha deficiency (2)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 3.16 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 33.97 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR012677 - Nucleotide-bd_a/b_plait
IPR000504 - RRM_dom

ModBase Predicted Comparative 3D Structure on B9ZVT1
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGDEnsembl   
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003676 nucleic acid binding
GO:0003723 RNA binding


-  Descriptions from all associated GenBank mRNAs
  BC039260 - Homo sapiens RNA binding motif protein 12B, mRNA (cDNA clone IMAGE:5288230), containing frame-shift errors.
KJ904264 - Synthetic construct Homo sapiens clone ccsbBroadEn_13658 RBM12B gene, encodes complete protein.

-  Other Names for This Gene
  Alternate Gene Symbols: B9ZVT1, B9ZVT1_HUMAN, BC039260, uc064oon.1
UCSC ID: uc064oon.1
Representative RNA: BC039260
Protein: B9ZVT1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.