Human Gene GPR39 (ENST00000622084.1) Description and Page Index
  Description: G protein-coupled receptor 39 (from HGNC GPR39)
RefSeq Summary (NM_001508): This gene is a member of the ghrelin receptor family and encodes a rhodopsin-type G-protein-coupled receptor (GPCR). The encoded protein is involved in zinc-dependent signaling in epithelial tissue in intestines, prostate and salivary glands. The protein may also be involved in the pathophysiology of depression. [provided by RefSeq, Jun 2016]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.30507.1, AK122643.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000329321.4/ ENSP00000327417.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##
Gencode Transcript: ENST00000622084.1
Gencode Gene: ENSG00000183840.7
Transcript (Including UTRs)
   Position: hg38 chr2:132,417,043-132,418,529 Size: 1,487 Total Exon Count: 2 Strand: +
Coding Region
   Position: hg38 chr2:132,417,043-132,418,529 Size: 1,487 Coding Exon Count: 2 

Page IndexSequence and LinksCTDRNA-Seq ExpressionMicroarray ExpressionOther Species
mRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr2:132,417,043-132,418,529)mRNA (may differ from genome)Protein (300 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
MGIPubMedStanford SOURCEUniProtKBWikipedia

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 1.66 RPKM in Colon - Transverse
Total median expression: 10.35 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence    

-  Descriptions from all associated GenBank mRNAs
  AK122643 - Homo sapiens cDNA FLJ16071 fis, clone HSYRA2001003, highly similar to Probable G-protein coupled receptor 39.
AK314895 - Homo sapiens cDNA, FLJ95798, highly similar to Homo sapiens G protein-coupled receptor 39 (GPR39), mRNA.
AB527984 - Synthetic construct DNA, clone: pF1KE0606, Homo sapiens GPR39 gene for G protein-coupled receptor 39, without stop codon, in Flexi system.
KJ891285 - Synthetic construct Homo sapiens clone ccsbBroadEn_00679 GPR39 gene, encodes complete protein.
AF034633 - Homo sapiens orphan G protein-coupled receptor (GPR39) mRNA, complete cds.
FJ348258 - Homo sapiens G protein-coupled receptor 39 (GPR39) mRNA, complete cds.
BC125046 - Homo sapiens G protein-coupled receptor 39, mRNA (cDNA clone MGC:149541 IMAGE:40116106), complete cds.
BC125047 - Homo sapiens G protein-coupled receptor 39, mRNA (cDNA clone IMAGE:40116108), partial cds.
EU076432 - Homo sapiens G-protein coupled receptor 39-1b mRNA, complete cds.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A087WTL7, AB527984, uc061nxm.1
UCSC ID: uc061nxm.1
RefSeq Accession: NM_001508

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.