Human Gene NADK2 (ENST00000617628.4) Description and Page Index
  Description: NAD kinase 2, mitochondrial (from HGNC NADK2)
RefSeq Summary (NM_001287340): This gene encodes a mitochondrial kinase that catalyzes the phosphorylation of NAD to yield NADP. Mutations in this gene result in 2,4-dienoyl-CoA reductase deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014].
Gencode Transcript: ENST00000617628.4
Gencode Gene: ENSG00000152620.13
Transcript (Including UTRs)
   Position: hg38 chr5:36,195,144-36,225,612 Size: 30,469 Total Exon Count: 8 Strand: -
Coding Region
   Position: hg38 chr5:36,195,144-36,225,612 Size: 30,469 Coding Exon Count: 8 

Page IndexSequence and LinksMalaCardsRNA-Seq ExpressionMicroarray ExpressionOther Species
mRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr5:36,195,144-36,225,612)mRNA (may differ from genome)Protein (247 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
EnsemblExonPrimerGeneCardsLynxMGIPubMed
Stanford SOURCEUniProtKB

-  MalaCards Disease Associations
  MalaCards Gene Search: NADK2
Diseases sorted by gene-association score: 2,4-dienoyl-coa reductase deficiency* (1331), hyperlysinemia (25)
* = Manually curated disease association

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 46.87 RPKM in Liver
Total median expression: 473.89 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Descriptions from all associated GenBank mRNAs
  BX648388 - Homo sapiens mRNA; cDNA DKFZp686J18205 (from clone DKFZp686J18205).
AK057950 - Homo sapiens cDNA FLJ25221 fis, clone STM00723.
BC062567 - Homo sapiens chromosome 5 open reading frame 33, mRNA (cDNA clone MGC:70464 IMAGE:5172232), complete cds.
AK055158 - Homo sapiens cDNA FLJ30596 fis, clone BRAWH2009227.
BC045565 - Homo sapiens chromosome 5 open reading frame 33, mRNA (cDNA clone IMAGE:4818838), containing frame-shift errors.
BC032912 - Homo sapiens chromosome 5 open reading frame 33, mRNA (cDNA clone IMAGE:5265328), complete cds.
AK304009 - Homo sapiens cDNA FLJ55867 complete cds.
AY360463 - Homo sapiens hypothetical protein FLJ30596-like protein mRNA, complete cds; alternatively spliced.
HQ448065 - Synthetic construct Homo sapiens clone IMAGE:100071444; CCSB012103_02 chromosome 5 open reading frame 33 (C5orf33) gene, encodes complete protein.
KJ895490 - Synthetic construct Homo sapiens clone ccsbBroadEn_04884 NADKD1 gene, encodes complete protein.
CU687562 - Synthetic construct Homo sapiens gateway clone IMAGE:100021680 5' read C5orf33 mRNA.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A0C4DGV3, AY360463, uc010iux.1, uc010iux.2, uc010iux.3, uc010iux.4, uc010iux.5
UCSC ID: uc010iux.5
RefSeq Accession: NM_001287340

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.