Human Gene NDUFB5 (ENST00000611971.4) Description and Page Index
Description: Homo sapiens NADH:ubiquinone oxidoreductase subunit B5 (NDUFB5), transcript variant 3, mRNA. (from RefSeq NM_001199958) RefSeq Summary (NM_001199958): The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]. Gencode Transcript: ENST00000611971.4 Gencode Gene: ENSG00000136521.13 Transcript (Including UTRs) Position: hg38 chr3:179,604,787-179,624,499 Size: 19,713 Total Exon Count: 5 Strand: + Coding Region Position: hg38 chr3:179,604,816-179,623,985 Size: 19,170 Coding Exon Count: 5
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.