Human Gene ZNF787 (ENST00000610935.2) Description and Page Index
  Description: Homo sapiens zinc finger protein 787 (ZNF787), transcript variant 1, mRNA. (from RefSeq NM_001002836)
Gencode Transcript: ENST00000610935.2
Gencode Gene: ENSG00000142409.6
Transcript (Including UTRs)
   Position: hg38 chr19:56,087,366-56,121,295 Size: 33,930 Total Exon Count: 3 Strand: -
Coding Region
   Position: hg38 chr19:56,088,023-56,103,217 Size: 15,195 Coding Exon Count: 2 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr19:56,087,366-56,121,295)mRNA (may differ from genome)Protein (382 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsHGNC
HPRDLynxMGIneXtProtPubMedStanford SOURCE

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Zinc finger protein 787; AltName: Full=TTF-I-interacting peptide 20;
FUNCTION: May be involved in transcriptional regulation.
SUBCELLULAR LOCATION: Nucleus (Potential).
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein family.
SIMILARITY: Contains 7 C2H2-type zinc fingers.
SEQUENCE CAUTION: Sequence=AAB58413.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 11.06 RPKM in Spleen
Total median expression: 331.57 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -63.30134-0.472 Picture PostScript Text
3' UTR -294.10657-0.448 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like
IPR013087 - Znf_C2H2/integrase_DNA-bd

Pfam Domains:
PF00096 - Zinc finger, C2H2 type

ModBase Predicted Comparative 3D Structure on Q6DD87
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0046872 metal ion binding

Biological Process:
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter

Cellular Component:
GO:0005634 nucleus

-  Descriptions from all associated GenBank mRNAs
  BC012495 - Homo sapiens, clone IMAGE:4477095, mRNA.
BC077728 - Homo sapiens zinc finger protein 787, mRNA (cDNA clone MGC:78664 IMAGE:6210543), complete cds.
AF000560 - Homo sapiens TTF-I interacting peptide 20 mRNA, partial cds.
BC058034 - Homo sapiens cDNA clone IMAGE:6571547, partial cds.
JD217789 - Sequence 198813 from Patent EP1572962.
JD252493 - Sequence 233517 from Patent EP1572962.
JD547109 - Sequence 528133 from Patent EP1572962.
JD186391 - Sequence 167415 from Patent EP1572962.
JD183591 - Sequence 164615 from Patent EP1572962.
JD522624 - Sequence 503648 from Patent EP1572962.
JD359392 - Sequence 340416 from Patent EP1572962.
JD209770 - Sequence 190794 from Patent EP1572962.
JD193986 - Sequence 175010 from Patent EP1572962.
JD124805 - Sequence 105829 from Patent EP1572962.
JD108658 - Sequence 89682 from Patent EP1572962.
BC037737 - Homo sapiens cDNA clone IMAGE:5269796, with apparent retained intron.
JD460812 - Sequence 441836 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_001002836, O00455, Q6DD87, uc032igd.1, uc032igd.2, ZN787_HUMAN
UCSC ID: uc032igd.2
RefSeq Accession: NM_001002836
Protein: Q6DD87 (aka ZN787_HUMAN)
CCDS: CCDS42634.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.