Human Gene TMEM101 (ENST00000589334.5) Description and Page Index
Description: Homo sapiens transmembrane protein 101 (TMEM101), transcript variant 3, mRNA. (from RefSeq NM_001304814)
Gencode Transcript: ENST00000589334.5
Gencode Gene: ENSG00000091947.10
Transcript (Including UTRs)
Position: hg38 chr17:44,011,188-44,023,151 Size: 11,964 Total Exon Count: 5 Strand: -
Position: hg38 chr17:44,011,928-44,014,952 Size: 3,025 Coding Exon Count: 4
Data last updated: 2019-09-04
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Transmembrane protein 101; AltName: Full=Putative NF-kappa-B-activating protein 130;
FUNCTION: May activate NF-kappa-B signaling pathways. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
ModBase Predicted Comparative 3D Structure on Q96IK0
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
LF209367 - JP 2014500723-A/16870: Polycomb-Associated Non-Coding RNAs. MA444944 - JP 2018138019-A/16870: Polycomb-Associated Non-Coding RNAs. BC007438 - Homo sapiens transmembrane protein 101, mRNA (cDNA clone MGC:4251 IMAGE:3028940), complete cds. AK130810 - Homo sapiens cDNA FLJ27300 fis, clone TMS04606. JD051606 - Sequence 32630 from Patent EP1572962. AK172826 - Homo sapiens cDNA FLJ23987 fis, clone HRC00739. AB097008 - Homo sapiens mRNA for putative NFkB activating protein, complete cds, clone: 130. JD379276 - Sequence 360300 from Patent EP1572962. JD077673 - Sequence 58697 from Patent EP1572962. JD423803 - Sequence 404827 from Patent EP1572962. JD089172 - Sequence 70196 from Patent EP1572962. JD469148 - Sequence 450172 from Patent EP1572962. JD073923 - Sequence 54947 from Patent EP1572962. JD075636 - Sequence 56660 from Patent EP1572962. JD050710 - Sequence 31734 from Patent EP1572962. JD454036 - Sequence 435060 from Patent EP1572962. JD311201 - Sequence 292225 from Patent EP1572962. LF328021 - JP 2014500723-A/135524: Polycomb-Associated Non-Coding RNAs. MA563598 - JP 2018138019-A/135524: Polycomb-Associated Non-Coding RNAs. JD066604 - Sequence 47628 from Patent EP1572962. AK294237 - Homo sapiens cDNA FLJ52143 complete cds, highly similar to Transmembrane protein 101. JD035675 - Sequence 16699 from Patent EP1572962. JD199546 - Sequence 180570 from Patent EP1572962. JD552051 - Sequence 533075 from Patent EP1572962. JD256240 - Sequence 237264 from Patent EP1572962. JD475009 - Sequence 456033 from Patent EP1572962. LF328022 - JP 2014500723-A/135525: Polycomb-Associated Non-Coding RNAs. MA563599 - JP 2018138019-A/135525: Polycomb-Associated Non-Coding RNAs. JD566117 - Sequence 547141 from Patent EP1572962. JD250689 - Sequence 231713 from Patent EP1572962. JD536258 - Sequence 517282 from Patent EP1572962. JD202483 - Sequence 183507 from Patent EP1572962. JD492137 - Sequence 473161 from Patent EP1572962. JD442529 - Sequence 423553 from Patent EP1572962. AK313855 - Homo sapiens cDNA, FLJ94484. HQ447373 - Synthetic construct Homo sapiens clone IMAGE:100070694; CCSB004633_01 transmembrane protein 101 (TMEM101) gene, encodes complete protein. KJ894990 - Synthetic construct Homo sapiens clone ccsbBroadEn_04384 TMEM101 gene, encodes complete protein. CU675657 - Synthetic construct Homo sapiens gateway clone IMAGE:100018631 5' read TMEM101 mRNA.
Other Names for This Gene
Alternate Gene Symbols: B2R9N6, NM_001304814, Q96IK0, TM101_HUMAN, uc002ieu.1, uc002ieu.2, uc002ieu.3, uc002ieu.4 UCSC ID: uc002ieu.4 RefSeq Accession: NM_001304813
(aka TM101_HUMAN) Q96IK0
Methods, Credits, and Use Restrictions
for details on how this gene model was made and data restrictions if any.