Human Gene GASK1B (ENST00000585682.5) Description and Page Index
  Description: Homo sapiens golgi associated kinase 1B (GASK1B), transcript variant 3, mRNA. (from RefSeq NM_001128424)
Gencode Transcript: ENST00000585682.5
Gencode Gene: ENSG00000164125.15
Transcript (Including UTRs)
   Position: hg38 chr4:158,124,474-158,173,050 Size: 48,577 Total Exon Count: 5 Strand: -
Coding Region
   Position: hg38 chr4:158,127,407-158,171,375 Size: 43,969 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr4:158,124,474-158,173,050)mRNA (may differ from genome)Protein (519 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerGeneCardsMGIneXtProtPubMed
Stanford SOURCEUniProtKBWikipedia

-  Comments and Description Text from UniProtKB
  ID: F198B_HUMAN
DESCRIPTION: RecName: Full=Protein FAM198B; AltName: Full=Expressed in nerve and epithelium during development;
SUBCELLULAR LOCATION: Golgi apparatus membrane; Single-pass type II membrane protein (Probable).
SIMILARITY: Belongs to the FAM198 family.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 77.09 RPKM in Adrenal Gland
Total median expression: 450.15 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -91.60407-0.225 Picture PostScript Text
3' UTR -613.602933-0.209 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q6UWH4
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  LF206148 - JP 2014500723-A/13651: Polycomb-Associated Non-Coding RNAs.
MA441725 - JP 2018138019-A/13651: Polycomb-Associated Non-Coding RNAs.
BC017701 - Homo sapiens chromosome 4 open reading frame 18, mRNA (cDNA clone IMAGE:4399420), complete cds.
AF260333 - Homo sapiens AD036 mRNA, complete cds.
AL834177 - Homo sapiens mRNA; cDNA DKFZp434L142 (from clone DKFZp434L142).
BC045710 - Homo sapiens chromosome 4 open reading frame 18, mRNA (cDNA clone IMAGE:4798067).
AL832589 - Homo sapiens mRNA; cDNA DKFZp451L1216 (from clone DKFZp451L1216).
AK095474 - Homo sapiens cDNA FLJ38155 fis, clone DFNES1000185.
JD248804 - Sequence 229828 from Patent EP1572962.
JD337341 - Sequence 318365 from Patent EP1572962.
JD225058 - Sequence 206082 from Patent EP1572962.
BC100016 - Homo sapiens chromosome 4 open reading frame 18, mRNA (cDNA clone IMAGE:5260703), partial cds.
BC043193 - Homo sapiens chromosome 4 open reading frame 18, mRNA (cDNA clone MGC:44228 IMAGE:5288748), complete cds.
JD082872 - Sequence 63896 from Patent EP1572962.
JD557134 - Sequence 538158 from Patent EP1572962.
JD075635 - Sequence 56659 from Patent EP1572962.
JD300671 - Sequence 281695 from Patent EP1572962.
JD132505 - Sequence 113529 from Patent EP1572962.
JD440465 - Sequence 421489 from Patent EP1572962.
JD352188 - Sequence 333212 from Patent EP1572962.
JD239338 - Sequence 220362 from Patent EP1572962.
LF351978 - JP 2014500723-A/159481: Polycomb-Associated Non-Coding RNAs.
MA587555 - JP 2018138019-A/159481: Polycomb-Associated Non-Coding RNAs.
JD305837 - Sequence 286861 from Patent EP1572962.
JD562677 - Sequence 543701 from Patent EP1572962.
LF351977 - JP 2014500723-A/159480: Polycomb-Associated Non-Coding RNAs.
MA587554 - JP 2018138019-A/159480: Polycomb-Associated Non-Coding RNAs.
AY358785 - Homo sapiens clone DNA98380 TCPD2512 (UNQ2512) mRNA, complete cds.
JD504153 - Sequence 485177 from Patent EP1572962.
JD298898 - Sequence 279922 from Patent EP1572962.
JD378925 - Sequence 359949 from Patent EP1572962.
LF351976 - JP 2014500723-A/159479: Polycomb-Associated Non-Coding RNAs.
MA587553 - JP 2018138019-A/159479: Polycomb-Associated Non-Coding RNAs.
JD208324 - Sequence 189348 from Patent EP1572962.
JD058510 - Sequence 39534 from Patent EP1572962.
LF351975 - JP 2014500723-A/159478: Polycomb-Associated Non-Coding RNAs.
MA587552 - JP 2018138019-A/159478: Polycomb-Associated Non-Coding RNAs.
AF223468 - Homo sapiens AD021 protein (AD021) mRNA, complete cds.
AK304112 - Homo sapiens cDNA FLJ61056 complete cds.
LF351974 - JP 2014500723-A/159477: Polycomb-Associated Non-Coding RNAs.
MA587551 - JP 2018138019-A/159477: Polycomb-Associated Non-Coding RNAs.
AK315768 - Homo sapiens cDNA, FLJ96881.
CU676026 - Synthetic construct Homo sapiens gateway clone IMAGE:100016875 5' read C4orf18 mRNA.
KJ902578 - Synthetic construct Homo sapiens clone ccsbBroadEn_11972 FAM198B gene, encodes complete protein.
AB527363 - Synthetic construct DNA, clone: pF1KE0308, Homo sapiens C4orf18 gene for chromosome 4 open reading frame 18, without stop codon, in Flexi system.
AM392540 - Synthetic construct Homo sapiens clone IMAGE:100002133 for hypothetical protein (C4orf18 gene).
AM392704 - Synthetic construct Homo sapiens clone IMAGE:100002134 for hypothetical protein (C4orf18 gene).
CR457196 - Homo sapiens full open reading frame cDNA clone RZPDo834F058D for gene DKFZp434L142, hypothetical protein DKFZp434L142; complete cds, incl. stopcodon.
LF351973 - JP 2014500723-A/159476: Polycomb-Associated Non-Coding RNAs.
MA587550 - JP 2018138019-A/159476: Polycomb-Associated Non-Coding RNAs.
LF351972 - JP 2014500723-A/159475: Polycomb-Associated Non-Coding RNAs.
MA587549 - JP 2018138019-A/159475: Polycomb-Associated Non-Coding RNAs.
LF351970 - JP 2014500723-A/159473: Polycomb-Associated Non-Coding RNAs.
MA587547 - JP 2018138019-A/159473: Polycomb-Associated Non-Coding RNAs.
LF351969 - JP 2014500723-A/159472: Polycomb-Associated Non-Coding RNAs.
MA587546 - JP 2018138019-A/159472: Polycomb-Associated Non-Coding RNAs.
LF351963 - JP 2014500723-A/159466: Polycomb-Associated Non-Coding RNAs.
MA587540 - JP 2018138019-A/159466: Polycomb-Associated Non-Coding RNAs.
LF351962 - JP 2014500723-A/159465: Polycomb-Associated Non-Coding RNAs.
MA587539 - JP 2018138019-A/159465: Polycomb-Associated Non-Coding RNAs.
AK172805 - Homo sapiens cDNA FLJ23966 fis, clone HEP16465.
LF351958 - JP 2014500723-A/159461: Polycomb-Associated Non-Coding RNAs.
MA587535 - JP 2018138019-A/159461: Polycomb-Associated Non-Coding RNAs.
LF351957 - JP 2014500723-A/159460: Polycomb-Associated Non-Coding RNAs.
MA587534 - JP 2018138019-A/159460: Polycomb-Associated Non-Coding RNAs.
JD057409 - Sequence 38433 from Patent EP1572962.
JD426472 - Sequence 407496 from Patent EP1572962.
JD466947 - Sequence 447971 from Patent EP1572962.
JD346976 - Sequence 328000 from Patent EP1572962.
JD276224 - Sequence 257248 from Patent EP1572962.
JD259226 - Sequence 240250 from Patent EP1572962.
JD200982 - Sequence 182006 from Patent EP1572962.
JD165522 - Sequence 146546 from Patent EP1572962.
LF351956 - JP 2014500723-A/159459: Polycomb-Associated Non-Coding RNAs.
MA587533 - JP 2018138019-A/159459: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: AD021, C4orf18, ENED, F198B_HUMAN, FAM198B, NM_001128424, Q498Z3, Q6IAF9, Q6UWH4, Q6ZMF2, Q86XL0, uc003ipr.1, uc003ipr.2, uc003ipr.3, uc003ipr.4, uc003ipr.5, UNQ2512/PRO6001
UCSC ID: uc003ipr.5
RefSeq Accession: NM_001128424
Protein: Q6UWH4 (aka F198B_HUMAN)
CCDS: CCDS3798.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.