Human Gene ZSCAN10 (ENST00000572548.1) Description and Page Index
  Description: Contains 1 SCAN box domain. (from UniProt I3NI43)
Gencode Transcript: ENST00000572548.1
Gencode Gene: ENSG00000130182.8
Transcript (Including UTRs)
   Position: hg38 chr16:3,090,552-3,099,261 Size: 8,710 Total Exon Count: 5 Strand: -
Coding Region
   Position: hg38 chr16:3,091,588-3,092,937 Size: 1,350 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA-Seq ExpressionRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr16:3,090,552-3,099,261)mRNA (may differ from genome)Protein (111 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
MGIPubMedStanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
DESCRIPTION: SubName: Full=Zinc finger and SCAN domain-containing protein 10;
SIMILARITY: Contains 1 SCAN box domain.
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 0.21 RPKM in Brain - Cerebellum
Total median expression: 1.01 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -48.90139-0.352 Picture PostScript Text
3' UTR -45.80143-0.320 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR008916 - Retrov_capsid_C
IPR003309 - Tscrpt_reg_SCAN

Pfam Domains:
PF02023 - SCAN domain

ModBase Predicted Comparative 3D Structure on I3NI43
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003700 transcription factor activity, sequence-specific DNA binding

Biological Process:
GO:0006355 regulation of transcription, DNA-templated

Cellular Component:
GO:0005634 nucleus

-  Descriptions from all associated GenBank mRNAs
  AK027455 - Homo sapiens cDNA FLJ14549 fis, clone NT2RM2001670, weakly similar to ZINC FINGER PROTEIN 29.
AK074736 - Homo sapiens cDNA FLJ90255 fis, clone NT2RM4000326, highly similar to Zinc finger protein 206.
BC114452 - Homo sapiens zinc finger and SCAN domain containing 10, mRNA (cDNA clone IMAGE:40007610), partial cds.
BC167837 - Synthetic construct Homo sapiens clone IMAGE:100068227, MGC:195844 zinc finger and SCAN domain containing 10 (ZSCAN10) mRNA, encodes complete protein.
BC111367 - Homo sapiens cDNA clone IMAGE:7481438.
JD542629 - Sequence 523653 from Patent EP1572962.
JD065514 - Sequence 46538 from Patent EP1572962.
JD477874 - Sequence 458898 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: BC111367, I3NI43, I3NI43_HUMAN, uc059pve.1, uc059pve.2
UCSC ID: uc059pve.2
RefSeq Accession: NM_001365272
Protein: I3NI43

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.