Human Gene NIP7 (ENST00000569637.6) Description and Page Index
  Description: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. (from UniProt J3QLW7)
Gencode Transcript: ENST00000569637.6
Gencode Gene: ENSG00000132603.15
Transcript (Including UTRs)
   Position: hg38 chr16:69,339,568-69,340,887 Size: 1,320 Total Exon Count: 3 Strand: +
Coding Region
   Position: hg38 chr16:69,339,830-69,340,383 Size: 554 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr16:69,339,568-69,340,887)mRNA (may differ from genome)Protein (110 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
MGIPubMedStanford SOURCEUniProtKBWikipedia

-  Comments and Description Text from UniProtKB
DESCRIPTION: SubName: Full=60S ribosome subunit biogenesis protein NIP7 homolog;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 16.54 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 248.12 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -85.20262-0.325 Picture PostScript Text
3' UTR -148.10504-0.294 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR016686 - Ribosomal_synth_fac_NIP7

ModBase Predicted Comparative 3D Structure on J3QLW7
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence    

-  Descriptions from all associated GenBank mRNAs
  AB112439 - Homo sapiens NIP7 mRNA for hypothetical protein, complete cds, clone: PDL2-26-1.
AK315355 - Homo sapiens cDNA, FLJ96400, Homo sapiens comparative gene identification transcript 37(CGI-37), mRNA.
BC015941 - Homo sapiens nuclear import 7 homolog (S. cerevisiae), mRNA (cDNA clone MGC:9263 IMAGE:3922688), complete cds.
AF085360 - Homo sapiens HSPC031 mRNA, complete cds.
AF132971 - Homo sapiens CGI-37 protein mRNA, complete cds.
AF161528 - Homo sapiens HSPC180 mRNA, complete cds.
JD341181 - Sequence 322205 from Patent EP1572962.
AB062398 - Homo sapiens OK/SW-cl.76 mRNA, complete cds.
AB062479 - Homo sapiens OK/SW-cl.78 mRNA, complete cds.
AK001158 - Homo sapiens cDNA FLJ10296 fis, clone NT2RM1001044, highly similar to Homo sapiens HSPC031 mRNA.
CU677525 - Synthetic construct Homo sapiens gateway clone IMAGE:100017975 5' read NIP7 mRNA.
DQ894291 - Synthetic construct Homo sapiens clone IMAGE:100008751; FLH169416.01L; RZPDo839C0295D nuclear import 7 homolog (S. cerevisiae) (NIP7) gene, encodes complete protein.
DQ891111 - Synthetic construct clone IMAGE:100003741; FLH169420.01X; RZPDo839C0296D nuclear import 7 homolog (S. cerevisiae) (NIP7) gene, encodes complete protein.
KJ893903 - Synthetic construct Homo sapiens clone ccsbBroadEn_03297 NIP7 gene, encodes complete protein.
JD019524 - Sequence 548 from Patent EP1572962.
DQ583345 - Homo sapiens piRNA piR-50457, complete sequence.
JD021655 - Sequence 2679 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: AB112439, J3QLW7, J3QLW7_HUMAN, uc059wkr.1
UCSC ID: uc059wkr.1
RefSeq Accession: NM_001199434
Protein: J3QLW7

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.