Human Gene ZBTB25 (ENST00000555220.5) Description and Page Index
  Description: Homo sapiens zinc finger and BTB domain containing 25 (ZBTB25), transcript variant 3, mRNA. (from RefSeq NM_001304508)
Gencode Transcript: ENST00000555220.5
Gencode Gene: ENSG00000089775.11
Transcript (Including UTRs)
   Position: hg38 chr14:64,449,106-64,505,213 Size: 56,108 Total Exon Count: 3 Strand: -
Coding Region
   Position: hg38 chr14:64,449,551-64,490,533 Size: 40,983 Coding Exon Count: 2 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr14:64,449,106-64,505,213)mRNA (may differ from genome)Protein (86 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsHGNC

-  Comments and Description Text from UniProtKB
DESCRIPTION: SubName: Full=Zinc finger and BTB domain-containing protein 25;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 6.17 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 113.55 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -352.70734-0.481 Picture PostScript Text
3' UTR -109.60445-0.246 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR000210 - BTB/POZ-like
IPR011333 - BTB/POZ_fold
IPR013069 - BTB_POZ

Pfam Domains:
PF00651 - BTB/POZ domain

ModBase Predicted Comparative 3D Structure on G3V2K3
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence    

-  Descriptions from all associated GenBank mRNAs
  BC014650 - Homo sapiens mRNA similar to zinc finger protein 46 (KUP) (cDNA clone IMAGE:4564508).
BC035804 - Homo sapiens zinc finger and BTB domain containing 25, mRNA (cDNA clone MGC:46128 IMAGE:5745935), complete cds.
AK098181 - Homo sapiens cDNA FLJ40862 fis, clone TRACH2018262, highly similar to Zinc finger and BTB domain-containing protein 25.
AK313889 - Homo sapiens cDNA, FLJ94524.
X16576 - Human KUP mRNA for protein with two zinc fingers.
JF432133 - Synthetic construct Homo sapiens clone IMAGE:100073273 zinc finger and BTB domain containing 25 (ZBTB25) gene, encodes complete protein.
KJ892409 - Synthetic construct Homo sapiens clone ccsbBroadEn_01803 ZBTB25 gene, encodes complete protein.
EU446912 - Synthetic construct Homo sapiens clone IMAGE:100070220; IMAGE:100012121; FLH257364.01L zinc finger and BTB domain containing 25 (ZBTB25) gene, encodes complete protein.
AB587459 - Synthetic construct DNA, clone: pF1KB8178, Homo sapiens ZBTB25 gene for zinc finger and BTB domain containing 25, without stop codon, in Flexi system.
LF384860 - JP 2014500723-A/192363: Polycomb-Associated Non-Coding RNAs.
MA620437 - JP 2018138019-A/192363: Polycomb-Associated Non-Coding RNAs.
LF329702 - JP 2014500723-A/137205: Polycomb-Associated Non-Coding RNAs.
MA565279 - JP 2018138019-A/137205: Polycomb-Associated Non-Coding RNAs.
CU690202 - Synthetic construct Homo sapiens gateway clone IMAGE:100019384 5' read ZBTB25 mRNA.

-  Other Names for This Gene
  Alternate Gene Symbols: G3V2K3, G3V2K3_HUMAN, NM_001304508, uc001xhc.1, uc001xhc.2, uc001xhc.3
UCSC ID: uc001xhc.3
RefSeq Accession: NM_001304508
Protein: G3V2K3 CCDS: CCDS76689.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.