Human Gene LRFN5 (ENST00000554120.5) Description and Page Index
Description: Contains 1 LRRCT domain. (from UniProt G3V4N1) RefSeq Summary (NM_001330106): This gene encodes a protein that belongs to the leucine-rich repeat and fibronectin type III domain-containing family of proteins. A similar protein in mouse, a glycosylated transmembrane protein, is thought to function in presynaptic differentiation. [provided by RefSeq, Sep 2016]. Gencode Transcript: ENST00000554120.5 Gencode Gene: ENSG00000165379.13 Transcript (Including UTRs) Position: hg38 chr14:41,608,415-41,904,549 Size: 296,135 Total Exon Count: 4 Strand: + Coding Region Position: hg38 chr14:41,886,626-41,904,170 Size: 17,545 Coding Exon Count: 2
ID:G3V4N1_HUMAN DESCRIPTION: SubName: Full=Leucine-rich repeat and fibronectin type-III domain-containing protein 5; SIMILARITY: Contains 1 LRRCT domain. SIMILARITY: Contains 1 LRRNT domain. CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on G3V4N1
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.