Human Gene ARHGAP27 (ENST00000532891.6) Description and Page Index
Description: Contains 1 PH domain. (from UniProt E9PIR1) RefSeq Summary (NM_001282290): This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may pay a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2013]. Gencode Transcript: ENST00000532891.6 Gencode Gene: ENSG00000159314.11 Transcript (Including UTRs) Position: hg38 chr17:45,395,456-45,430,279 Size: 34,824 Total Exon Count: 16 Strand: - Coding Region Position: hg38 chr17:45,395,456-45,430,279 Size: 34,824 Coding Exon Count: 16
ID:E9PIR1_HUMAN DESCRIPTION: SubName: Full=Rho GTPase-activating protein 27; SIMILARITY: Contains 1 PH domain. SIMILARITY: Contains 1 Rho-GAP domain. CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
ModBase Predicted Comparative 3D Structure on E9PIR1
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.