Human Gene GATD1 (ENST00000524550.5) Description and Page Index
  Description: Homo sapiens glutamine amidotransferase like class 1 domain containing 1 (GATD1), transcript variant 7, mRNA. (from RefSeq NM_001318824)
Gencode Transcript: ENST00000524550.5
Gencode Gene: ENSG00000177225.17
Transcript (Including UTRs)
   Position: hg38 chr11:770,470-777,475 Size: 7,006 Total Exon Count: 7 Strand: -
Coding Region
   Position: hg38 chr11:770,897-777,462 Size: 6,566 Coding Exon Count: 7 

Page IndexSequence and LinksUniProtKB CommentsRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:770,470-777,475)mRNA (may differ from genome)Protein (184 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerGeneCardsHPRDLynxMGI
neXtProtPubMedStanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: PDDC1_HUMAN
DESCRIPTION: RecName: Full=Parkinson disease 7 domain-containing protein 1; Flags: Precursor;
SUBCELLULAR LOCATION: Secreted (Potential).
SIMILARITY: Belongs to the peptidase C56 family.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 25.03 RPKM in Brain - Cerebellar Hemisphere
Total median expression: 684.07 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
3' UTR -191.60427-0.449 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR002818 - ThiJ/PfpI

Pfam Domains:
PF01965 - DJ-1/PfpI family

ModBase Predicted Comparative 3D Structure on Q8NB37
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGI Ensembl   
Protein Sequence     
Alignment     

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003674 molecular_function

Biological Process:
GO:0008150 biological_process

Cellular Component:
GO:0005576 extracellular region
GO:0070062 extracellular exosome


-  Descriptions from all associated GenBank mRNAs
  BC110868 - Homo sapiens Parkinson disease 7 domain containing 1, mRNA (cDNA clone MGC:131881 IMAGE:5726838), complete cds.
AK091602 - Homo sapiens cDNA FLJ34283 fis, clone FEBRA2003926, weakly similar to NonF.
AX747087 - Sequence 612 from Patent EP1308459.
AK092816 - Homo sapiens cDNA FLJ35497 fis, clone SMINT2008869.
AX747745 - Sequence 1270 from Patent EP1308459.
AK128653 - Homo sapiens cDNA FLJ46812 fis, clone TRACH3036278.
AK094678 - Homo sapiens cDNA FLJ37359 fis, clone BRAMY2023238.
KJ904221 - Synthetic construct Homo sapiens clone ccsbBroadEn_13615 PDDC1 gene, encodes complete protein.
AK293559 - Homo sapiens cDNA FLJ53027 complete cds, highly similar to Mus musculus Parkinson disease 7 domain containing 1 (Pddc1), mRNA.
LF207968 - JP 2014500723-A/15471: Polycomb-Associated Non-Coding RNAs.
MA443545 - JP 2018138019-A/15471: Polycomb-Associated Non-Coding RNAs.
AK309153 - Homo sapiens cDNA, FLJ99194.
LF370566 - JP 2014500723-A/178069: Polycomb-Associated Non-Coding RNAs.
MA606143 - JP 2018138019-A/178069: Polycomb-Associated Non-Coding RNAs.
BC143419 - Homo sapiens cDNA clone IMAGE:9051927.
BC112145 - Homo sapiens Parkinson disease 7 domain containing 1, mRNA (cDNA clone MGC:138350 IMAGE:8327613), complete cds.
BC143415 - Homo sapiens cDNA clone IMAGE:9051923.
BC143416 - Homo sapiens Parkinson disease 7 domain containing 1, mRNA (cDNA clone MGC:176941 IMAGE:9051924), complete cds.
BC143418 - Homo sapiens Parkinson disease 7 domain containing 1, mRNA (cDNA clone MGC:176943 IMAGE:9051926), complete cds.
BC143421 - Homo sapiens cDNA clone IMAGE:9051929.
BC143423 - Homo sapiens cDNA clone IMAGE:9051931.
BC143420 - Homo sapiens Parkinson disease 7 domain containing 1, mRNA (cDNA clone MGC:176945 IMAGE:9051928), complete cds.
BC143422 - Homo sapiens cDNA clone IMAGE:9051930.
LF370567 - JP 2014500723-A/178070: Polycomb-Associated Non-Coding RNAs.
MA606144 - JP 2018138019-A/178070: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: B7ZKW5, NM_001318824, PDDC1, PDDC1_HUMAN, Q2NL76, Q6ZQY0, Q8NAE0, Q8NB37, uc057xln.1
UCSC ID: uc057xln.1
RefSeq Accession: NM_001318824
Protein: Q8NB37 (aka PDDC1_HUMAN)
CCDS: CCDS81530.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.