Human Gene HYI (ENST00000486909.1) Description and Page Index
Description: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. (from UniProt E7EWH8) RefSeq Summary (NM_001190880): This gene encodes a putative hydroxypyruvate isomerase, which likely catalyzes the conversion of hydroxypyruvate to 2-hydroxy-3-oxopropanoate, and may be involved in carbohydrate transport and metabolism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]. Gencode Transcript: ENST00000486909.1 Gencode Gene: ENSG00000178922.16 Transcript (Including UTRs) Position: hg38 chr1:43,451,320-43,453,848 Size: 2,529 Total Exon Count: 7 Strand: - Coding Region Position: hg38 chr1:43,451,339-43,453,793 Size: 2,455 Coding Exon Count: 7
ID:E7EWH8_HUMAN DESCRIPTION: SubName: Full=Putative hydroxypyruvate isomerase; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF01261 - Xylose isomerase-like TIM barrel
ModBase Predicted Comparative 3D Structure on E7EWH8
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.