Human Gene CLLU1 (ENST00000472839.6) Description and Page Index
  Description: Homo sapiens chronic lymphocytic leukemia up-regulated 1 (CLLU1), transcript variant 2, long non-coding RNA. (from RefSeq NR_027932)
RefSeq Summary (NR_027932): Expression of this gene has been shown to be upregulated in some individuals with chronic lymphocytic leukemia (CLL), and has been used for prognostic and diagnostic purposes. This gene was originally identified as a human-specific putative protein-coding gene due to the presence of a peptide (PAp00140670, HIIYSTFLSK) that could have supported translation at this locus. This peptide is not present in more recent builds of PeptideAtlas, and the presence of a protein product at this locus has not been independently verified. For this reason, this gene is being represented as non-coding. Sequence comparisons to other primates indicates that no other primate is predicted to contain an open reading frame. [provided by RefSeq, Feb 2017].
Gencode Transcript: ENST00000472839.6
Gencode Gene: ENSG00000257127.6
Transcript (Including UTRs)
   Position: hg38 chr12:92,421,531-92,430,988 Size: 9,458 Total Exon Count: 3 Strand: +


Page IndexSequence and LinksMalaCardsRNA-Seq ExpressionMicroarray ExpressionOther Species
mRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:92,421,531-92,430,988)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSCGAP
EnsemblEntrez GeneExonPrimerHGNCLynxOMIM
PubMedStanford SOURCE

-  MalaCards Disease Associations
  MalaCards Gene Search: CLLU1
Diseases sorted by gene-association score: chronic lymphocytic leukemia (25), leukemia (13)

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 0.11 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 0.20 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AJ845167 - Homo sapiens mRNA for non-coding transcript (CLLU1 gene), splice variant 6.
AJ845163 - Homo sapiens mRNA for non-coding transcript (CLLU1 gene), splice variant 2.
CQ819405 - Sequence 6 from Patent WO2004046376.
CQ819406 - Sequence 7 from Patent WO2004046376.
CQ819410 - Sequence 11 from Patent WO2004046376.
AJ845162 - Homo sapiens mRNA for non-coding transcript (CLLU1 gene), splice variant 1.
AJ845164 - Homo sapiens mRNA for non-coding transcript (CLLU1 gene), splice variant 3.
CQ819407 - Sequence 8 from Patent WO2004046376.
CQ819418 - Sequence 19 from Patent WO2004046376.
CQ819403 - Sequence 4 from Patent WO2004046376.
CQ819419 - Sequence 20 from Patent WO2004046376.
AJ845166 - Homo sapiens mRNA for CLLU1 protein (CLLU1 gene), splice variant 5.
AJ845165 - Homo sapiens mRNA for CLLU1 protein (CLLU1 gene), splice variant 4.
CQ819409 - Sequence 10 from Patent WO2004046376.
CQ819401 - Sequence 2 from Patent WO2004046376.
CQ819420 - Sequence 21 from Patent WO2004046376.
CQ819421 - Sequence 22 from Patent WO2004046376.
CQ819422 - Sequence 23 from Patent WO2004046376.

-  Other Names for This Gene
  Alternate Gene Symbols: NR_027932, uc001tcc.1, uc001tcc.2, uc001tcc.3
UCSC ID: uc001tcc.3
RefSeq Accession: NR_027932

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.