Human Gene ESRP1 (ENST00000454170.7) Description and Page Index
  Description: Homo sapiens epithelial splicing regulatory protein 1 (ESRP1), transcript variant 5, mRNA. (from RefSeq NM_001122827)
RefSeq Summary (NM_001122827): ESPR1 is an epithelial cell-type-specific splicing regulator (Warzecha et al., 2009 [PubMed 19285943]).[supplied by OMIM, Aug 2009].
Gencode Transcript: ENST00000454170.7
Gencode Gene: ENSG00000104413.18
Transcript (Including UTRs)
   Position: hg38 chr8:94,641,204-94,707,466 Size: 66,263 Total Exon Count: 14 Strand: +
Coding Region
   Position: hg38 chr8:94,641,319-94,705,931 Size: 64,613 Coding Exon Count: 14 

Page IndexSequence and LinksMalaCardsCTDRNA-Seq ExpressionMicroarray Expression
RNA StructureOther SpeciesmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr8:94,641,204-94,707,466)mRNA (may differ from genome)Protein (604 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsHGNC

-  MalaCards Disease Associations
  MalaCards Gene Search: ESRP1
Diseases sorted by gene-association score: chromophobe renal cell carcinoma (3)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 36.19 RPKM in Esophagus - Mucosa
Total median expression: 251.65 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -16.40115-0.143 Picture PostScript Text
3' UTR -338.101535-0.220 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence    

-  Descriptions from all associated GenBank mRNAs
  BX647570 - Homo sapiens mRNA; cDNA DKFZp313K1811 (from clone DKFZp313K1811).
BC099916 - Homo sapiens epithelial splicing regulatory protein 1, mRNA (cDNA clone MGC:104725 IMAGE:30527936), complete cds.
BC067098 - Homo sapiens epithelial splicing regulatory protein 1, mRNA (cDNA clone MGC:71203 IMAGE:6586195), complete cds.
BC019932 - Homo sapiens epithelial splicing regulatory protein 1, mRNA (cDNA clone IMAGE:4991420), partial cds.
BC052574 - Homo sapiens cDNA clone IMAGE:6586439, containing frame-shift errors.
KJ899023 - Synthetic construct Homo sapiens clone ccsbBroadEn_08417 ESRP1 gene, encodes complete protein.
KJ906202 - Synthetic construct Homo sapiens clone ccsbBroadEn_15872 ESRP1 gene, encodes complete protein.
BC035406 - Homo sapiens RNA binding motif protein 35A, mRNA (cDNA clone IMAGE:4526804).
AK000178 - Homo sapiens cDNA FLJ20171 fis, clone COL09761.
BC101621 - Homo sapiens cDNA clone IMAGE:8069127.
BC112043 - Homo sapiens epithelial splicing regulatory protein 1, mRNA (cDNA clone IMAGE:8327511), partial cds.
AK001805 - Homo sapiens cDNA FLJ10943 fis, clone OVARC1001360.
JD128657 - Sequence 109681 from Patent EP1572962.
JD537460 - Sequence 518484 from Patent EP1572962.
JD053308 - Sequence 34332 from Patent EP1572962.
JD062521 - Sequence 43545 from Patent EP1572962.
JD359486 - Sequence 340510 from Patent EP1572962.
JD187186 - Sequence 168210 from Patent EP1572962.
BX641160 - Homo sapiens mRNA; cDNA DKFZp686M05238 (from clone DKFZp686M05238).
JD267733 - Sequence 248757 from Patent EP1572962.
JD306787 - Sequence 287811 from Patent EP1572962.
JD297726 - Sequence 278750 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A2U3TZN9, NM_001122827, uc286aug.1
UCSC ID: uc286aug.1
RefSeq Accession: NM_001122827
CCDS: CCDS47896.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.