Human Gene OSBPL9 (ENST00000453295.5) Description and Page Index
Description: Homo sapiens oxysterol binding protein like 9 (OSBPL9), transcript variant 3, mRNA. (from RefSeq NM_148906) RefSeq Summary (NM_148906): This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function. Multiple transcript variants, most of which encode distinct isoforms, have been identified. Related pseudogenes have been identified on chromosomes 3, 11 and 12. [provided by RefSeq, Jul 2010]. Gencode Transcript: ENST00000453295.5 Gencode Gene: ENSG00000117859.19 Transcript (Including UTRs) Position: hg38 chr1:51,617,109-51,788,469 Size: 171,361 Total Exon Count: 23 Strand: + Coding Region Position: hg38 chr1:51,617,111-51,787,789 Size: 170,679 Coding Exon Count: 23
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q96SU4
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.