Human Gene ELP6 (ENST00000446787.5) Description and Page Index
  Description: Homo sapiens elongator acetyltransferase complex subunit 6 (ELP6), transcript variant 2, mRNA. (from RefSeq NM_001363957)
Gencode Transcript: ENST00000446787.5
Gencode Gene: ENSG00000163832.16
Transcript (Including UTRs)
   Position: hg38 chr3:47,495,946-47,511,215 Size: 15,270 Total Exon Count: 6 Strand: -
Coding Region
   Position: hg38 chr3:47,496,069-47,504,433 Size: 8,365 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr3:47,495,946-47,511,215)mRNA (may differ from genome)Protein (193 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsHGNC
LynxMGImyGene2OMIMPubMedStanford SOURCE

-  Comments and Description Text from UniProtKB
DESCRIPTION: SubName: Full=Elongator complex protein 6;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 13.53 RPKM in Testis
Total median expression: 334.45 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -47.20189-0.250 Picture PostScript Text
3' UTR -30.50123-0.248 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR018627 - UPF0405

Pfam Domains:
PF09807 - Elongation complex protein 6

ModBase Predicted Comparative 3D Structure on C9IYN7
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Biological Process:
GO:0002098 tRNA wobble uridine modification

Cellular Component:
GO:0033588 Elongator holoenzyme complex

-  Descriptions from all associated GenBank mRNAs
  KJ902704 - Synthetic construct Homo sapiens clone ccsbBroadEn_12098 C3orf75 gene, encodes complete protein.
BC000623 - Homo sapiens chromosome 3 open reading frame 75, mRNA (cDNA clone MGC:1068 IMAGE:3346325), complete cds.
BC014204 - Homo sapiens chromosome 3 open reading frame 75, mRNA (cDNA clone MGC:20645 IMAGE:4620013), complete cds.
AK225721 - Homo sapiens mRNA for hypothetical protein LOC54859 isoform 2 variant, clone: TMS09262.
AK298202 - Homo sapiens cDNA FLJ54324 complete cds.
DQ787088 - Homo sapiens angiotonin transactivated protein 1 (ATP1) mRNA, complete cds.
AK000218 - Homo sapiens cDNA FLJ20211 fis, clone COLF1807.

-  Other Names for This Gene
  Alternate Gene Symbols: C9IYN7, C9IYN7_HUMAN, NM_001363957, uc062jds.1
UCSC ID: uc062jds.1
RefSeq Accession: NM_001031703
Protein: C9IYN7

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.