Human Gene TOGARAM1 (ENST00000361577.7) Description and Page Index
  Description: Homo sapiens TOG array regulator of axonemal microtubules 1 (TOGARAM1), transcript variant 2, mRNA. (from RefSeq NM_015091)
Gencode Transcript: ENST00000361577.7
Gencode Gene: ENSG00000198718.13
Transcript (Including UTRs)
   Position: hg38 chr14:44,962,208-45,074,431 Size: 112,224 Total Exon Count: 19 Strand: +
Coding Region
   Position: hg38 chr14:44,962,422-45,073,561 Size: 111,140 Coding Exon Count: 19 

Page IndexSequence and LinksUniProtKB CommentsRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr14:44,962,208-45,074,431)mRNA (may differ from genome)Protein (1720 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerGeneCardsHPRDLynxMGI
neXtProtOMIMPubMedStanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: F179B_HUMAN
DESCRIPTION: RecName: Full=Protein FAM179B;
SIMILARITY: Belongs to the FAM179 family.
SIMILARITY: Contains 6 HEAT repeats.
SEQUENCE CAUTION: Sequence=BAA24853.2; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=CAH18354.1; Type=Frameshift; Positions=1069, 1506;

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 9.32 RPKM in Brain - Cerebellar Hemisphere
Total median expression: 245.78 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -92.10214-0.430 Picture PostScript Text
3' UTR -159.60870-0.183 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR011989 - ARM-like
IPR016024 - ARM-type_fold

ModBase Predicted Comparative 3D Structure on Q9Y4F4
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Biological Process:
GO:0030030 cell projection organization
GO:0031116 positive regulation of microtubule polymerization
GO:0035082 axoneme assembly
GO:1905515 non-motile cilium assembly

Cellular Component:
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005929 cilium
GO:0036064 ciliary basal body
GO:0042995 cell projection
GO:0005874 microtubule


-  Descriptions from all associated GenBank mRNAs
  AK295185 - Homo sapiens cDNA FLJ52098 complete cds.
AB007883 - Homo sapiens KIAA0423 mRNA.
CR749557 - Homo sapiens mRNA; cDNA DKFZp686D12126 (from clone DKFZp686D12126).
BC057255 - Homo sapiens family with sequence similarity 179, member B, mRNA (cDNA clone MGC:51232 IMAGE:5274847), complete cds.
AK096934 - Homo sapiens cDNA FLJ39615 fis, clone SMINT2000468.
AK311034 - Homo sapiens cDNA, FLJ18076.
JD076855 - Sequence 57879 from Patent EP1572962.
AK307722 - Homo sapiens cDNA, FLJ97670.
BX648723 - Homo sapiens mRNA; cDNA DKFZp686H2147 (from clone DKFZp686H2147).
JD407146 - Sequence 388170 from Patent EP1572962.
JD462454 - Sequence 443478 from Patent EP1572962.
JD073140 - Sequence 54164 from Patent EP1572962.
JD167502 - Sequence 148526 from Patent EP1572962.
JD528729 - Sequence 509753 from Patent EP1572962.
JD288756 - Sequence 269780 from Patent EP1572962.
JD250904 - Sequence 231928 from Patent EP1572962.
BC065234 - Homo sapiens family with sequence similarity 179, member B, mRNA (cDNA clone IMAGE:6161345), partial cds.
JD027475 - Sequence 8499 from Patent EP1572962.
JD515884 - Sequence 496908 from Patent EP1572962.
JD156004 - Sequence 137028 from Patent EP1572962.
JD224155 - Sequence 205179 from Patent EP1572962.
JD359312 - Sequence 340336 from Patent EP1572962.
JD237976 - Sequence 219000 from Patent EP1572962.
JD244144 - Sequence 225168 from Patent EP1572962.
JD296347 - Sequence 277371 from Patent EP1572962.
JD488477 - Sequence 469501 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: F179B_HUMAN, FAM179B, KIAA0423, NM_015091, Q68D66, Q6PG27, Q9Y4F4, uc001wvv.1, uc001wvv.2, uc001wvv.3, uc001wvv.4
UCSC ID: uc001wvv.4
RefSeq Accession: NM_015091
Protein: Q9Y4F4 (aka F179B_HUMAN)
CCDS: CCDS9681.1, CCDS76676.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.