Human Gene TOGARAM1 (ENST00000361577.7) Description and Page Index
  Description: Homo sapiens TOG array regulator of axonemal microtubules 1 (TOGARAM1), transcript variant 2, mRNA. (from RefSeq NM_015091)
Gencode Transcript: ENST00000361577.7
Gencode Gene: ENSG00000198718.13
Transcript (Including UTRs)
   Position: hg38 chr14:44,962,208-45,074,431 Size: 112,224 Total Exon Count: 19 Strand: +
Coding Region
   Position: hg38 chr14:44,962,422-45,073,561 Size: 111,140 Coding Exon Count: 19 

Page IndexSequence and LinksUniProtKB CommentsRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr14:44,962,208-45,074,431)mRNA (may differ from genome)Protein (1720 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerGeneCardsHPRDLynxMGI
neXtProtOMIMPubMedStanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Protein FAM179B;
SIMILARITY: Belongs to the FAM179 family.
SIMILARITY: Contains 6 HEAT repeats.
SEQUENCE CAUTION: Sequence=BAA24853.2; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=CAH18354.1; Type=Frameshift; Positions=1069, 1506;

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 9.32 RPKM in Brain - Cerebellar Hemisphere
Total median expression: 245.78 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -92.10214-0.430 Picture PostScript Text
3' UTR -159.60870-0.183 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR011989 - ARM-like
IPR016024 - ARM-type_fold

ModBase Predicted Comparative 3D Structure on Q9Y4F4
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Biological Process:
GO:0030030 cell projection organization
GO:0031116 positive regulation of microtubule polymerization
GO:0035082 axoneme assembly
GO:1905515 non-motile cilium assembly

Cellular Component:
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005929 cilium
GO:0036064 ciliary basal body
GO:0042995 cell projection
GO:0005874 microtubule

-  Descriptions from all associated GenBank mRNAs
  AK295185 - Homo sapiens cDNA FLJ52098 complete cds.
AB007883 - Homo sapiens KIAA0423 mRNA.
CR749557 - Homo sapiens mRNA; cDNA DKFZp686D12126 (from clone DKFZp686D12126).
BC057255 - Homo sapiens family with sequence similarity 179, member B, mRNA (cDNA clone MGC:51232 IMAGE:5274847), complete cds.
AK096934 - Homo sapiens cDNA FLJ39615 fis, clone SMINT2000468.
AK311034 - Homo sapiens cDNA, FLJ18076.
JD076855 - Sequence 57879 from Patent EP1572962.
AK307722 - Homo sapiens cDNA, FLJ97670.
BX648723 - Homo sapiens mRNA; cDNA DKFZp686H2147 (from clone DKFZp686H2147).
JD407146 - Sequence 388170 from Patent EP1572962.
JD462454 - Sequence 443478 from Patent EP1572962.
JD073140 - Sequence 54164 from Patent EP1572962.
JD167502 - Sequence 148526 from Patent EP1572962.
JD528729 - Sequence 509753 from Patent EP1572962.
JD288756 - Sequence 269780 from Patent EP1572962.
JD250904 - Sequence 231928 from Patent EP1572962.
BC065234 - Homo sapiens family with sequence similarity 179, member B, mRNA (cDNA clone IMAGE:6161345), partial cds.
JD027475 - Sequence 8499 from Patent EP1572962.
JD515884 - Sequence 496908 from Patent EP1572962.
JD156004 - Sequence 137028 from Patent EP1572962.
JD224155 - Sequence 205179 from Patent EP1572962.
JD359312 - Sequence 340336 from Patent EP1572962.
JD237976 - Sequence 219000 from Patent EP1572962.
JD244144 - Sequence 225168 from Patent EP1572962.
JD296347 - Sequence 277371 from Patent EP1572962.
JD488477 - Sequence 469501 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: F179B_HUMAN, FAM179B, KIAA0423, NM_015091, Q68D66, Q6PG27, Q9Y4F4, uc001wvv.1, uc001wvv.2, uc001wvv.3, uc001wvv.4
UCSC ID: uc001wvv.4
RefSeq Accession: NM_015091
Protein: Q9Y4F4 (aka F179B_HUMAN)
CCDS: CCDS9681.1, CCDS76676.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.