Human Gene ZNF511 (ENST00000361518.10) Description and Page Index
  Description: Homo sapiens zinc finger protein 511 (ZNF511), transcript variant 2, non-coding RNA. (from RefSeq NR_130127)
Gencode Transcript: ENST00000361518.10
Gencode Gene: ENSG00000198546.15
Transcript (Including UTRs)
   Position: hg38 chr10:133,308,914-133,313,161 Size: 4,248 Total Exon Count: 6 Strand: +
Coding Region
   Position: hg38 chr10:133,308,944-133,312,866 Size: 3,923 Coding Exon Count: 6 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA-Seq ExpressionRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr10:133,308,914-133,313,161)mRNA (may differ from genome)Protein (252 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsHGNC
HPRDLynxMGIneXtProtPubMedStanford SOURCE

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Zinc finger protein 511;
FUNCTION: May be involved in transcriptional regulation.
SUBCELLULAR LOCATION: Nucleus (Potential).
SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein family.
SIMILARITY: Contains 3 C2H2-type zinc fingers.
SEQUENCE CAUTION: Sequence=AAH15139.1; Type=Erroneous initiation;

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 24.08 RPKM in Uterus
Total median expression: 771.49 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -9.5030-0.317 Picture PostScript Text
3' UTR -98.20295-0.333 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like
IPR013087 - Znf_C2H2/integrase_DNA-bd

ModBase Predicted Comparative 3D Structure on Q8NB15
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologGenome BrowserNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence Protein Sequence  
AlignmentAlignment Alignment  

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046872 metal ion binding

Biological Process:
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter

Cellular Component:
GO:0005634 nucleus

-  Descriptions from all associated GenBank mRNAs
  BC015139 - Homo sapiens zinc finger protein 511, mRNA (cDNA clone IMAGE:4040789), partial cds.
BC019897 - Homo sapiens zinc finger protein 511, mRNA (cDNA clone MGC:30006 IMAGE:5123355), complete cds.
AK091711 - Homo sapiens cDNA FLJ34392 fis, clone HCHON2000265.
AX747142 - Sequence 667 from Patent EP1308459.
AK292380 - Homo sapiens cDNA FLJ78327 complete cds.
JF432478 - Synthetic construct Homo sapiens clone IMAGE:100073699 zinc finger protein 511 (ZNF511) gene, encodes complete protein.
KJ895336 - Synthetic construct Homo sapiens clone ccsbBroadEn_04730 ZNF511 gene, encodes complete protein.
EU937518 - Homo sapiens ZNF511/PRAP1 fusion protein mRNA, complete cds.
JD050024 - Sequence 31048 from Patent EP1572962.
JD498798 - Sequence 479822 from Patent EP1572962.
JD165496 - Sequence 146520 from Patent EP1572962.
JD072601 - Sequence 53625 from Patent EP1572962.
JD437209 - Sequence 418233 from Patent EP1572962.
JD525833 - Sequence 506857 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A8K8L5, NR_130127, Q8NB15, Q8WUP1, Q96BV2, uc001lmj.1, uc001lmj.2, uc001lmj.3, ZN511_HUMAN
UCSC ID: uc001lmj.3
RefSeq Accession: NM_145806
Protein: Q8NB15 (aka ZN511_HUMAN)
CCDS: CCDS7677.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.