Human Gene ZNF112 (ENST00000337401.8) Description and Page Index
Description: Homo sapiens zinc finger protein 112 (ZNF112), transcript variant 1, mRNA. (from RefSeq NM_001083335)
Gencode Transcript: ENST00000337401.8
Gencode Gene: ENSG00000062370.16
Transcript (Including UTRs)
Position: hg38 chr19:44,326,943-44,356,680 Size: 29,738 Total Exon Count: 5 Strand: -
Position: hg38 chr19:44,327,433-44,343,268 Size: 15,836 Coding Exon Count: 4
Data last updated: 2019-09-04
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Zinc finger protein 112 homolog; Short=Zfp-112; AltName: Full=Zinc finger protein 228;
FUNCTION: May be involved in transcriptional regulation. SUBCELLULAR LOCATION: Nucleus (Probable). SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein family. SIMILARITY: Contains 17 C2H2-type zinc fingers. SIMILARITY: Contains 1 KRAB domain.
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR001909 - Krueppel-associated_box
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like
IPR013087 - Znf_C2H2/integrase_DNA-bd
Pfam Domains: PF01352 - KRAB box
ModBase Predicted Comparative 3D Structure on Q9UJU3
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AL122078 - Homo sapiens mRNA; cDNA DKFZp434J0650 (from clone DKFZp434J0650); partial cds. AK026230 - Homo sapiens cDNA: FLJ22577 fis, clone HSI02514, highly similar to AF198358 Homo sapiens zinc finger protein ZNF228 (ZNF228) mRNA. AF198358 - Homo sapiens zinc finger protein ZNF228 (ZNF228) mRNA, complete cds. AK023099 - Homo sapiens cDNA FLJ13037 fis, clone NT2RP3001268, highly similar to Zinc finger protein 228. AK130371 - Homo sapiens cDNA FLJ26861 fis, clone PRS08385, highly similar to Zinc finger protein 228. JD410350 - Sequence 391374 from Patent EP1572962. JD559151 - Sequence 540175 from Patent EP1572962. JD507071 - Sequence 488095 from Patent EP1572962. JD532052 - Sequence 513076 from Patent EP1572962. JD302437 - Sequence 283461 from Patent EP1572962. AK302966 - Homo sapiens cDNA FLJ55602 complete cds, highly similar to Zinc finger protein 228. JD435840 - Sequence 416864 from Patent EP1572962. JD550452 - Sequence 531476 from Patent EP1572962. BC101753 - Homo sapiens zinc finger protein 112 homolog (mouse), mRNA (cDNA clone MGC:126802 IMAGE:8069259), complete cds. BC117223 - Homo sapiens zinc finger protein 112 homolog (mouse), mRNA (cDNA clone MGC:150832 IMAGE:40125774), complete cds. AK302594 - Homo sapiens cDNA FLJ55559 complete cds, highly similar to Zinc finger protein 228. HQ258527 - Synthetic construct Homo sapiens clone IMAGE:100072956 zinc finger protein 112 homolog (mouse) (ZFP112), transcript variant 2 (ZFP112) gene, encodes complete protein. KJ897784 - Synthetic construct Homo sapiens clone ccsbBroadEn_07178 ZFP112 gene, encodes complete protein.
Biochemical and Signaling Pathways
Other Names for This Gene
Alternate Gene Symbols: A4FU53, NM_001083335, Q9HCA7, Q9UJU3, uc010ejj.1, uc010ejj.2, uc010ejj.3, uc010ejj.4, ZF112_HUMAN, ZFP112, ZNF228 UCSC ID: uc010ejj.4 RefSeq Accession: NM_001083335
(aka ZF112_HUMAN) Q9UJU3
CCDS: CCDS12637.1, CCDS54276.1
Methods, Credits, and Use Restrictions
for details on how this gene model was made and data restrictions if any.