Human Gene ETNK1 (ENST00000335148.8) Description and Page Index
Description: Homo sapiens ethanolamine kinase 1 (ETNK1), transcript variant 2, mRNA. (from RefSeq NM_001039481) RefSeq Summary (NM_001039481): This gene encodes an ethanolamine kinase, which functions in the first committed step of the phosphatidylethanolamine synthesis pathway. This cytosolic enzyme is specific for ethanolamine and exhibits negligible kinase activity on choline. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000335148.8 Gencode Gene: ENSG00000139163.16 Transcript (Including UTRs) Position: hg38 chr12:22,625,141-22,644,587 Size: 19,447 Total Exon Count: 3 Strand: + Coding Region Position: hg38 chr12:22,625,431-22,644,304 Size: 18,874 Coding Exon Count: 3
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9HBU6
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.