Human Gene TMEM144 (ENST00000296529.11) Description and Page Index
Description: Homo sapiens transmembrane protein 144 (TMEM144), mRNA. (from RefSeq NM_018342)
Gencode Transcript: ENST00000296529.11
Gencode Gene: ENSG00000164124.11
Transcript (Including UTRs)
Position: hg38 chr4:158,210,486-158,255,416 Size: 44,931 Total Exon Count: 13 Strand: +
Position: hg38 chr4:158,212,668-158,253,527 Size: 40,860 Coding Exon Count: 11
Data last updated: 2019-09-04
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Transmembrane protein 144;
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential). SIMILARITY: Belongs to the TMEM144 family.
Comparative Toxicogenomics Database (CTD)
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
Press "+" in the title bar above to open this section.
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR012435 - DUF1632_TMEM144
Pfam Domains: PF07857 - Transmembrane family, TMEM144 of transporters
ModBase Predicted Comparative 3D Structure on Q7Z5S9
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0015144 carbohydrate transmembrane transporter activity
Biological Process: GO:0034219 carbohydrate transmembrane transport
Cellular Component: GO:0016020 membrane
GO:0016021 integral component of membrane
Descriptions from all associated GenBank mRNAs
LP896320 - Sequence 1184 from Patent EP3253886. LP895492 - Sequence 356 from Patent EP3253886. BC036551 - Homo sapiens transmembrane protein 144, mRNA (cDNA clone IMAGE:5264816), complete cds. BC048117 - Homo sapiens transmembrane protein 144, mRNA (cDNA clone IMAGE:5264713), complete cds. BC054487 - Homo sapiens transmembrane protein 144, mRNA (cDNA clone MGC:51851 IMAGE:5732836), complete cds. BC060875 - Homo sapiens transmembrane protein 144, mRNA (cDNA clone MGC:71832 IMAGE:4800219), complete cds. BC035811 - Homo sapiens transmembrane protein 144, mRNA (cDNA clone IMAGE:5754243). BC026318 - Homo sapiens transmembrane protein 144, mRNA (cDNA clone IMAGE:4799382). AK002017 - Homo sapiens cDNA FLJ11155 fis, clone PLACE1006935. JD322323 - Sequence 303347 from Patent EP1572962. JD021648 - Sequence 2672 from Patent EP1572962. JD028921 - Sequence 9945 from Patent EP1572962. CU691090 - Synthetic construct Homo sapiens gateway clone IMAGE:100021385 5' read TMEM144 mRNA. CU687490 - Synthetic construct Homo sapiens gateway clone IMAGE:100021114 5' read TMEM144 mRNA. HQ448479 - Synthetic construct Homo sapiens clone IMAGE:100071911; CCSB010956_01 transmembrane protein 144 (TMEM144) gene, encodes complete protein. KJ894183 - Synthetic construct Homo sapiens clone ccsbBroadEn_03577 TMEM144 gene, encodes complete protein. KJ899119 - Synthetic construct Homo sapiens clone ccsbBroadEn_08513 TMEM144 gene, encodes complete protein. BC050297 - Homo sapiens transmembrane protein 144, mRNA (cDNA clone IMAGE:5299592), with apparent retained intron. JD370698 - Sequence 351722 from Patent EP1572962. JD507892 - Sequence 488916 from Patent EP1572962. JD374964 - Sequence 355988 from Patent EP1572962. JD345923 - Sequence 326947 from Patent EP1572962. JD404102 - Sequence 385126 from Patent EP1572962. JD373783 - Sequence 354807 from Patent EP1572962. JD497479 - Sequence 478503 from Patent EP1572962. JD541902 - Sequence 522926 from Patent EP1572962. JD452476 - Sequence 433500 from Patent EP1572962. JD466572 - Sequence 447596 from Patent EP1572962. JD544124 - Sequence 525148 from Patent EP1572962. JD199015 - Sequence 180039 from Patent EP1572962. JD061544 - Sequence 42568 from Patent EP1572962. JD043986 - Sequence 25010 from Patent EP1572962. JD066553 - Sequence 47577 from Patent EP1572962. JD180939 - Sequence 161963 from Patent EP1572962. JD305044 - Sequence 286068 from Patent EP1572962. JD241726 - Sequence 222750 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: D3DP24, NM_018342, Q49A05, Q7Z5S9, Q9NUT3, TM144_HUMAN, uc003ipx.1, uc003ipx.2, uc003ipx.3, uc003ipx.4, uc003ipx.5 UCSC ID: uc003ipx.5 RefSeq Accession: NM_018342
(aka TM144_HUMAN) Q7Z5S9
Methods, Credits, and Use Restrictions
for details on how this gene model was made and data restrictions if any.