Human Gene DNAJC5G (ENST00000296097.8) Description and Page Index
  Description: Homo sapiens DnaJ heat shock protein family (Hsp40) member C5 gamma (DNAJC5G), transcript variant 1, mRNA. (from RefSeq NM_173650)
Gencode Transcript: ENST00000296097.8
Gencode Gene: ENSG00000163793.13
Transcript (Including UTRs)
   Position: hg38 chr2:27,275,433-27,281,499 Size: 6,067 Total Exon Count: 7 Strand: +
Coding Region
   Position: hg38 chr2:27,276,729-27,280,215 Size: 3,487 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA-Seq ExpressionRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr2:27,275,433-27,281,499)mRNA (may differ from genome)Protein (189 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsHGNC
Stanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=DnaJ homolog subfamily C member 5G; AltName: Full=Cysteine string protein-gamma; Short=CSP-gamma;
SUBCELLULAR LOCATION: Membrane; Lipid-anchor (By similarity).
TISSUE SPECIFICITY: Testis specific.
PTM: Palmitoylated (By similarity).
SIMILARITY: Contains 1 J domain.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 21.25 RPKM in Testis
Total median expression: 28.66 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -140.80406-0.347 Picture PostScript Text
3' UTR -298.501089-0.274 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001623 - DnaJ_N
IPR018253 - Heat_shock_DnaJ_CS
IPR003095 - Hsp_DnaJ

Pfam Domains:
PF00226 - DnaJ domain

ModBase Predicted Comparative 3D Structure on Q8N7S2
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0016020 membrane

-  Descriptions from all associated GenBank mRNAs
  AK097736 - Homo sapiens cDNA FLJ40417 fis, clone TESTI2038388, highly similar to Homo sapiens gamma cysteine string protein mRNA.
JD310519 - Sequence 291543 from Patent EP1572962.
AK311597 - Homo sapiens cDNA, FLJ18639.
BC035194 - Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 5 gamma, mRNA (cDNA clone MGC:43393 IMAGE:5266688), complete cds.
AK302239 - Homo sapiens cDNA FLJ51561 complete cds, weakly similar to DnaJ homolog subfamily C member 5G.
JD396333 - Sequence 377357 from Patent EP1572962.
JD087649 - Sequence 68673 from Patent EP1572962.
JD395767 - Sequence 376791 from Patent EP1572962.
JD144617 - Sequence 125641 from Patent EP1572962.
JD472382 - Sequence 453406 from Patent EP1572962.
JD332344 - Sequence 313368 from Patent EP1572962.
JD448327 - Sequence 429351 from Patent EP1572962.
JD523410 - Sequence 504434 from Patent EP1572962.
JD406748 - Sequence 387772 from Patent EP1572962.
JD405471 - Sequence 386495 from Patent EP1572962.
AF368277 - Homo sapiens gamma cysteine string protein mRNA, partial cds.
JD205401 - Sequence 186425 from Patent EP1572962.
JD068342 - Sequence 49366 from Patent EP1572962.
JD187188 - Sequence 168212 from Patent EP1572962.
JD390572 - Sequence 371596 from Patent EP1572962.
JD363356 - Sequence 344380 from Patent EP1572962.
JD095666 - Sequence 76690 from Patent EP1572962.
JD181513 - Sequence 162537 from Patent EP1572962.
JD358817 - Sequence 339841 from Patent EP1572962.
JD252182 - Sequence 233206 from Patent EP1572962.
JD157776 - Sequence 138800 from Patent EP1572962.
JD196712 - Sequence 177736 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: DNJ5G_HUMAN, NM_173650, Q53SY5, Q8IYQ4, Q8N7S2, Q96RJ8, uc002rjl.1, uc002rjl.2, uc002rjl.3
UCSC ID: uc002rjl.3
RefSeq Accession: NM_173650
Protein: Q8N7S2 (aka DNJ5G_HUMAN or DJ5G_HUMAN)
CCDS: CCDS1744.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.