Human Gene DNAJC5G (ENST00000296097.8) Description and Page Index
  Description: Homo sapiens DnaJ heat shock protein family (Hsp40) member C5 gamma (DNAJC5G), transcript variant 1, mRNA. (from RefSeq NM_173650)
Gencode Transcript: ENST00000296097.8
Gencode Gene: ENSG00000163793.13
Transcript (Including UTRs)
   Position: hg38 chr2:27,275,433-27,281,499 Size: 6,067 Total Exon Count: 7 Strand: +
Coding Region
   Position: hg38 chr2:27,276,729-27,280,215 Size: 3,487 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA-Seq ExpressionRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr2:27,275,433-27,281,499)mRNA (may differ from genome)Protein (189 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsHGNC
HPRDLynxMGIneXtProtOMIMPubMed
Stanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: DNJ5G_HUMAN
DESCRIPTION: RecName: Full=DnaJ homolog subfamily C member 5G; AltName: Full=Cysteine string protein-gamma; Short=CSP-gamma;
SUBCELLULAR LOCATION: Membrane; Lipid-anchor (By similarity).
TISSUE SPECIFICITY: Testis specific.
PTM: Palmitoylated (By similarity).
SIMILARITY: Contains 1 J domain.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 21.25 RPKM in Testis
Total median expression: 28.66 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -140.80406-0.347 Picture PostScript Text
3' UTR -298.501089-0.274 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001623 - DnaJ_N
IPR018253 - Heat_shock_DnaJ_CS
IPR003095 - Hsp_DnaJ

Pfam Domains:
PF00226 - DnaJ domain

ModBase Predicted Comparative 3D Structure on Q8N7S2
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0016020 membrane


-  Descriptions from all associated GenBank mRNAs
  AK097736 - Homo sapiens cDNA FLJ40417 fis, clone TESTI2038388, highly similar to Homo sapiens gamma cysteine string protein mRNA.
JD310519 - Sequence 291543 from Patent EP1572962.
AK311597 - Homo sapiens cDNA, FLJ18639.
BC035194 - Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 5 gamma, mRNA (cDNA clone MGC:43393 IMAGE:5266688), complete cds.
AK302239 - Homo sapiens cDNA FLJ51561 complete cds, weakly similar to DnaJ homolog subfamily C member 5G.
JD396333 - Sequence 377357 from Patent EP1572962.
JD087649 - Sequence 68673 from Patent EP1572962.
JD395767 - Sequence 376791 from Patent EP1572962.
JD144617 - Sequence 125641 from Patent EP1572962.
JD472382 - Sequence 453406 from Patent EP1572962.
JD332344 - Sequence 313368 from Patent EP1572962.
JD448327 - Sequence 429351 from Patent EP1572962.
JD523410 - Sequence 504434 from Patent EP1572962.
JD406748 - Sequence 387772 from Patent EP1572962.
JD405471 - Sequence 386495 from Patent EP1572962.
AF368277 - Homo sapiens gamma cysteine string protein mRNA, partial cds.
JD205401 - Sequence 186425 from Patent EP1572962.
JD068342 - Sequence 49366 from Patent EP1572962.
JD187188 - Sequence 168212 from Patent EP1572962.
JD390572 - Sequence 371596 from Patent EP1572962.
JD363356 - Sequence 344380 from Patent EP1572962.
JD095666 - Sequence 76690 from Patent EP1572962.
JD181513 - Sequence 162537 from Patent EP1572962.
JD358817 - Sequence 339841 from Patent EP1572962.
JD252182 - Sequence 233206 from Patent EP1572962.
JD157776 - Sequence 138800 from Patent EP1572962.
JD196712 - Sequence 177736 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: DNJ5G_HUMAN, NM_173650, Q53SY5, Q8IYQ4, Q8N7S2, Q96RJ8, uc002rjl.1, uc002rjl.2, uc002rjl.3
UCSC ID: uc002rjl.3
RefSeq Accession: NM_173650
Protein: Q8N7S2 (aka DNJ5G_HUMAN or DJ5G_HUMAN)
CCDS: CCDS1744.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.