Human Gene HNRNPU (ENST00000283179.14) Description and Page Index
Description: heterogeneous nuclear ribonucleoprotein U (from HGNC HNRNPU) RefSeq Summary (NM_004501): This gene encodes a member of a family of proteins that bind nucleic acids and function in the formation of ribonucleoprotein complexes in the nucleus with heterogeneous nuclear RNA (hnRNA). The encoded protein has affinity for both RNA and DNA, and binds scaffold-attached region (SAR) DNA. Mutations in this gene have been associated with epileptic encephalopathy, early infantile, 54. A pseudogene of this gene has been identified on chromosome 14. [provided by RefSeq, Jun 2017]. Gencode Transcript: ENST00000283179.14 Gencode Gene: ENSG00000153187.20 Transcript (Including UTRs) Position: hg38 chr1:244,853,752-244,864,494 Size: 10,743 Total Exon Count: 12 Strand: - Coding Region Position: hg38 chr1:244,854,450-244,864,307 Size: 9,858 Coding Exon Count: 12
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.