Human Gene HNRNPUL1 (ENST00000263367.7) Description and Page Index
  Description: Homo sapiens heterogeneous nuclear ribonucleoprotein U like 1 (HNRNPUL1), transcript variant 5, mRNA. (from RefSeq NM_001301016)
RefSeq Summary (NM_001301016): This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus early-1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by early-1B-55kDa in adenovirus-infected cells. [provided by RefSeq, Mar 2016].
Gencode Transcript: ENST00000263367.7
Gencode Gene: ENSG00000105323.17
Transcript (Including UTRs)
   Position: hg38 chr19:41,265,122-41,307,019 Size: 41,898 Total Exon Count: 15 Strand: +
Coding Region
   Position: hg38 chr19:41,265,316-41,306,565 Size: 41,250 Coding Exon Count: 15 

Page IndexSequence and LinksCTDRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr19:41,265,122-41,307,019)mRNA (may differ from genome)Protein (767 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsHGNC
LynxMGIOMIMPubMedStanford SOURCEUniProtKB
Wikipedia

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 55.28 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 1512.97 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -75.20194-0.388 Picture PostScript Text
3' UTR -137.61454-0.303 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001870 - B30.2/SPRY
IPR008985 - ConA-like_lec_gl_sf
IPR018355 - SPla/RYanodine_receptor_subgr
IPR003877 - SPRY_rcpt

Pfam Domains:
PF00622 - SPRY domain

ModBase Predicted Comparative 3D Structure on B7Z4B8
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGDEnsembl   
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Biological Process:
GO:0006396 RNA processing
GO:0009615 response to virus

Cellular Component:
GO:0005654 nucleoplasm


-  Descriptions from all associated GenBank mRNAs
  AK225850 - Homo sapiens mRNA for E1B-55kDa-associated protein 5 isoform a variant, clone: FCC125H07.
AK023006 - Homo sapiens cDNA FLJ12944 fis, clone NT2RP2005168, highly similar to Homo sapiens mRNA for E1B-55kDa-associated protein.
AK308078 - Homo sapiens cDNA, FLJ98026.
AJ007509 - Homo sapiens mRNA for E1B-55kDa-associated protein.
AK291762 - Homo sapiens cDNA FLJ78252 complete cds, highly similar to Homo sapiens heterogeneous nuclear ribonucleoprotein U-like 1 (HNRPUL1), transcript variant 1, mRNA.
AK127057 - Homo sapiens cDNA FLJ45114 fis, clone BRAWH3034775, highly similar to Homo sapiens E1B-55kDa-associated protein 5 (E1B-AP5).
AK022863 - Homo sapiens cDNA FLJ12801 fis, clone NT2RP2002099, highly similar to Heterogeneous nuclear ribonucleoprotein U-like protein 1.
AK308156 - Homo sapiens cDNA, FLJ98104.
BC009988 - Homo sapiens heterogeneous nuclear ribonucleoprotein U-like 1, mRNA (cDNA clone MGC:16706 IMAGE:4127873), complete cds.
AK291315 - Homo sapiens cDNA FLJ78309 complete cds, highly similar to Homo sapiens heterogeneous nuclear ribonucleoprotein U-like 1 (HNRPUL1), transcript variant 1, mRNA.
BC002564 - Homo sapiens heterogeneous nuclear ribonucleoprotein U-like 1, mRNA (cDNA clone MGC:1974 IMAGE:3139049), complete cds.
BC014232 - Homo sapiens heterogeneous nuclear ribonucleoprotein U-like 1, mRNA (cDNA clone MGC:20910 IMAGE:4558792), complete cds.
BC027713 - Homo sapiens heterogeneous nuclear ribonucleoprotein U-like 1, mRNA (cDNA clone MGC:16645 IMAGE:4123077), complete cds.
BC004242 - Homo sapiens heterogeneous nuclear ribonucleoprotein U-like 1, mRNA (cDNA clone IMAGE:3619753), complete cds.
AB384748 - Synthetic construct DNA, clone: pF1KB3100, Homo sapiens HNRPUL1 gene for heterogeneous nuclear ribonucleoprotein U-like protein 1, complete cds, without stop codon, in Flexi system.
EU831487 - Synthetic construct Homo sapiens clone HAIB:100066516; DKFZo008H0517 heterogeneous nuclear ribonucleoprotein U-like 1 protein (HNRPUL1) gene, encodes complete protein.
EU831574 - Synthetic construct Homo sapiens clone HAIB:100066603; DKFZo004H0518 heterogeneous nuclear ribonucleoprotein U-like 1 protein (HNRPUL1) gene, encodes complete protein.
KJ898356 - Synthetic construct Homo sapiens clone ccsbBroadEn_07750 HNRNPUL1 gene, encodes complete protein.
KJ902200 - Synthetic construct Homo sapiens clone ccsbBroadEn_11594 HNRNPUL1 gene, encodes complete protein.
KJ906068 - Synthetic construct Homo sapiens clone ccsbBroadEn_15738 HNRNPUL1 gene, encodes complete protein.
AK290729 - Homo sapiens cDNA FLJ75163 complete cds, highly similar to Homo sapiens heterogeneous nuclear ribonucleoprotein U-like 1 (HNRPUL1), transcript variant 4, mRNA.
AK297127 - Homo sapiens cDNA FLJ56481 complete cds, highly similar to Heterogeneous nuclear ribonucleoprotein U-like protein 1.
KJ898355 - Synthetic construct Homo sapiens clone ccsbBroadEn_07749 HNRNPUL1 gene, encodes complete protein.
EU831452 - Synthetic construct Homo sapiens clone HAIB:100066481; DKFZo008E0417 heterogeneous nuclear ribonucleoprotein U-like 1 protein (HNRPUL1) gene, encodes complete protein.
EU831539 - Synthetic construct Homo sapiens clone HAIB:100066568; DKFZo004E0418 heterogeneous nuclear ribonucleoprotein U-like 1 protein (HNRPUL1) gene, encodes complete protein.
CU693286 - Synthetic construct Homo sapiens gateway clone IMAGE:100023203 5' read HNRPUL1 mRNA.
CU678042 - Synthetic construct Homo sapiens gateway clone IMAGE:100020484 5' read HNRPUL1 mRNA.
CU679555 - Synthetic construct Homo sapiens gateway clone IMAGE:100020433 5' read HNRPUL1 mRNA.
AL050146 - Homo sapiens mRNA; cDNA DKFZp586D0920 (from clone DKFZp586D0920).
AK001229 - Homo sapiens cDNA FLJ10367 fis, clone NT2RM2001424, highly similar to Heterogeneous nuclear ribonucleoprotein U-like protein 1.
AK021455 - Homo sapiens cDNA FLJ11393 fis, clone HEMBA1000591, weakly similar to PTB-ASSOCIATED SPLICING FACTOR.
JD407938 - Sequence 388962 from Patent EP1572962.
JD336550 - Sequence 317574 from Patent EP1572962.
JD089081 - Sequence 70105 from Patent EP1572962.
JD108824 - Sequence 89848 from Patent EP1572962.
JD359453 - Sequence 340477 from Patent EP1572962.
JD547131 - Sequence 528155 from Patent EP1572962.
JD415822 - Sequence 396846 from Patent EP1572962.
JD556611 - Sequence 537635 from Patent EP1572962.
BC000860 - Homo sapiens heterogeneous nuclear ribonucleoprotein U-like 1, mRNA (cDNA clone IMAGE:3459524).
U55217 - Human RNA fragment from patients with Crohn's disease and ulcerative colitis.
JD520090 - Sequence 501114 from Patent EP1572962.
JD095178 - Sequence 76202 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: B7Z4B8, B7Z4B8_HUMAN, NM_001301016, uc060yzm.1
UCSC ID: uc060yzm.1
RefSeq Accession: NM_001301016
Protein: B7Z4B8 CCDS: CCDS12577.1, CCDS82351.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.