Human Gene RSPH14 (ENST00000216036.9) Description and Page Index
Description: Homo sapiens radial spoke head 14 homolog (RSPH14), mRNA. (from RefSeq NM_014433) RefSeq Summary (NM_014433): This gene encodes a protein with no known function but with slight similarity to a yeast vacuolar protein. The gene is located in a region deleted in pediatric rhabdoid tumors of the brain, kidney and soft tissues, but mutations in this gene have not been associated with the disease. [provided by RefSeq, Jul 2008]. ##Evidence-Data-START## Transcript exon combination :: AF133587.1, BC008986.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2158188 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000216036.9/ ENSP00000216036.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## Gencode Transcript: ENST00000216036.9 Gencode Gene: ENSG00000100218.12 Transcript (Including UTRs) Position: hg38 chr22:23,059,415-23,141,990 Size: 82,576 Total Exon Count: 7 Strand: - Coding Region Position: hg38 chr22:23,059,462-23,140,420 Size: 80,959 Coding Exon Count: 6
ID:RTDR1_HUMAN DESCRIPTION: RecName: Full=Rhabdoid tumor deletion region protein 1; TISSUE SPECIFICITY: Expressed in adult cerebellum, spinal cord, spleen, skeletal muscle and some/5 out of 9 rhabdoid tumors. Detected in fetal brain, lung, liver and kidney.
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Highest median expression: 11.88 RPKM in Testis
Total median expression: 32.73 RPKM
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9UHP6
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.