Human Gene TEX30 (uc001vpn.3)
  Description: Homo sapiens testis expressed 30 (TEX30), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr13:103,418,463-103,422,620 Size: 4,158 Total Exon Count: 4 Strand: -
Coding Region
   Position: hg19 chr13:103,418,751-103,421,783 Size: 3,033 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsPrimersMalaCardsCTD
Gene AllelesRNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther Species
GO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr13:103,418,463-103,422,620)mRNA (may differ from genome)Protein (186 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkH-INVHGNCHPRDLynxMalacards
MGIneXtProtPubMedTreefamUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: TEX30_HUMAN
DESCRIPTION: RecName: Full=Testis-expressed sequence 30 protein;
SEQUENCE CAUTION: Sequence=AAH15148.2; Type=Erroneous initiation; Sequence=CAI14521.1; Type=Erroneous gene model prediction;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: TEX30
Diseases sorted by gene-association score: rectal neoplasm (3)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 59.06 RPKM in Testis
Total median expression: 194.26 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -197.90837-0.236 Picture PostScript Text
3' UTR -47.80288-0.166 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR026555 - NSL3/Tex30

Pfam Domains:
PF01738 - Dienelactone hydrolase family

SCOP Domains:
53474 - alpha/beta-Hydrolases

ModBase Predicted Comparative 3D Structure on Q5JUR7
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0016787 hydrolase activity


-  Descriptions from all associated GenBank mRNAs
  AF070559 - Homo sapiens clone 24463 mRNA sequence.
BC048011 - Homo sapiens chromosome 13 open reading frame 27, mRNA (cDNA clone IMAGE:5296361).
BC015148 - Homo sapiens chromosome 13 open reading frame 27, mRNA (cDNA clone MGC:26637 IMAGE:4825712), complete cds.
AK314995 - Homo sapiens cDNA, FLJ95922.
HQ448335 - Synthetic construct Homo sapiens clone IMAGE:100071753; CCSB001388_02 chromosome 13 open reading frame 27 (C13orf27) gene, encodes complete protein.
KJ903593 - Synthetic construct Homo sapiens clone ccsbBroadEn_12987 TEX30 gene, encodes complete protein.

-  Other Names for This Gene
  Alternate Gene Symbols: AF070559, C13orf27, NM_138779, NP_620134, Q5JUR7, Q96KZ8, TEX30_HUMAN
UCSC ID: uc001vpn.3
RefSeq Accession: NM_138779
Protein: Q5JUR7 (aka TEX30_HUMAN)
CCDS: CCDS66577.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: AF070559.1
exon count: 4CDS single in 3' UTR: no RNA size: 1708
ORF size: 561CDS single in intron: no Alignment % ID: 99.94
txCdsPredict score: 962.50frame shift in genome: no % Coverage: 98.71
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: yes # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.